• Publications
  • Influence
Risk of venous thromboembolism in users of hormone replacement therapy
Current HRT use is associated with risk of VTE and the increased risk may be concentrated in new users, which needs to be weighed against the probable benefits of long-term treatment. Expand
A prospective study of acute cerebrovascular disease in the community: the Oxfordshire Community Stroke Project 1981-86. 1. Methodology, demography and incident cases of first-ever stroke.
The study protocol combined rapid clinical assessment of patients with accurate diagnosis of the pathological type of stroke by CT or necropsy, whether or not they were admitted to hospital, to ensure complete case ascertainment. Expand
Epidemiology of genital prolapse: observations from the Oxford Family Planning Association study
The epidemiology of uterovaginal and post‐hysterectomy prolapse and its role in women's health is studied to explore the causes and treatments of prolapse. Expand
Alcohol, tobacco and breast cancer – collaborative reanalysis of individual data from 53 epidemiological studies, including 58 515 women with breast cancer and 95 067 women without the disease
In conclusion, smoking has little or no independent effect on the risk of developing breast cancer; the effect of alcohol on breast cancer needs to be interpreted in the context of its beneficial effects, in moderation, on cardiovascular disease and its harmful effects on cirrhosis. Expand
Risk factors for uterine fibroids: reduced risk associated with oral contraceptives.
Investigation of risk factors for pathologically confirmed uterine leiomyomas (fibroids) in the Oxford Family Planning Association study showed that reproductive experiences were closely linked to development of fibroids, suggesting that the underlying risk factor is "unopposed" oestrogen. Expand
Polycystic ovaries and associated clinical and biochemical features in young women
To determine the prevalence of polycystic ovaries as identified by ultrasound in a group of young, postmenarcheal women in the normal population, and to investigate how polycystic ovaries are relatedExpand
The community prevalence of chronic pelvic pain in women and associated illness behaviour.
A high community prevalence of chronic pelvic pain in women of reproductive age was showed and a high rate of symptom-related anxiety was found in women with chronic pelvicPain compared with women with dysmenorrhoea. Expand
Prevalence and incidence of chronic pelvic pain in primary care: evidence from a national general practice database
The prevalence and incidence in primary care of chronic pelvic pain in women in the UK is estimated to be about 1 in 10,000, with a higher prevalence in women aged 40 and over. Expand
Routine follow up of breast cancer in primary care: randomised trial
General practice follow up of women with breast cancer in remission is not associated with increase in time to diagnosis, increase in anxiety, or deterioration in health related quality of life. Expand
Intensive Care Society's APACHE II study in Britain and Ireland--II: Outcome comparisons of intensive care units after adjustment for case mix by the American APACHE II method.
The American APACHE II equation did not fit the British and Irish data, and use of the American equation could be of advantage or disadvantage to individual intensive care units, depending on the mix of patients treated. Expand