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Urinary excretion in the rat of nifurpipone (NP) and of nitrofurantoin (NTF) administered by different routes.
Study of the Morphofunctional Alterations Produced by Fenticonazole on Strains of Candida albicans, using the Scanning Electron Microscope (S. E. M.)
The biological characterization of the substance which probably exhibits a block of enzymatic activity (cytochrome oxidase and peroxidase) as primordial cause of the structural and functional modifications observed is studied.
Fenticonazole, a new imidazole derivative with antibacterial and antifungal activity. In vitro study.
Fenticonazole showed in vitro at pH range 4-5 the highest activity against yeasts, and showed an excellent activity against gram-positive microorganisms.
Antifungal activity of fenticonazole in experimental dermatomycosis and candidiasis.
Fenticonazole proved to be a very active drug with a healing capacity generally higher than that of the reference compounds, giving complete healing without relapses in 100% of cases treated.
Humoral antibody, plaque, and rosette formation in mice treated with thiamphenicol and chloramphenicol.
Humoral antibody (anti-sheep haemagglutinin and haemolysin) production, and in vitro plaque and rosette formation by spleen cells in mice, assayed 4 days after a single intraperiton
Fenticonazole: A New Antifungal Imidazole Derivative In Vitro and In Vivo Antimycotic Activity
Summary: The activity of α‐(2,4‐dichlorophenyl)‐β, N‐imidazolylethyl 4‐phenylthiobenzyl ether nitrate (Fenticonazole) compared with those of reference standard drugs, was tested in vitro, in solid…
New alpha-aryl-beta,N-imidzolylethyl benzyl and naphthylmethyl ethers with antimycotic and antibacterial activity.
- D. Nardi, R. Cappelletti, A. Catto, A. Leonardi, A. Tajana, M. Veronese
- Chemistry, BiologyArzneimittel-Forschung
- 27 April 1982
A new series of alpha-aryl-beta,N-imidazolylethyl benzyl and naphthylmethyl ethers was synthesized and tested for antimycotic and antimicrobial activity; most of them showed antifungal activity, whereas no activity was detected against gram-negative bacteria.
Morphologic and biochemical characterization of Crithidia brasiliensis sp. n.
- M. de Sá, C. D. de Sá, M. Veronese, S. Filho, E. Gander
- BiologyThe Journal of protozoology
- 1 August 1980
A trypanosomatid with a choanomastigote stage and, therefore, belonging to the genus Crithidia, was isolated in culture from the alimentary tract of the hemipteran genus Zelus and appears to belong in a new species for which the name Crithidium brasiliensis sp.
Experimental studies in vitro and in vivo on the mutagenicity of flavoxate.
In the experimental conditions, flavoxate HCl was found to be devoid of potential mutagenic activity.