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- Publications
- Influence
Subnormothermic machine perfusion protects steatotic livers against preservation injury: A potential for donor pool increase?
- M. Vairetti, A. Ferrigno, +7 authors U. Cillo
- Medicine
- Liver transplantation : official publication of…
- 1 January 2009
We tested whether rat liver preservation performed by machine perfusion (MP) at 20°C can enhance the functional integrity of steatotic livers versus simple cold storage. We also compared MP at 20°C… Expand
Demonstration of nuclear compartmentalization of glutathione in hepatocytes.
- G. Bellomo, M. Vairetti, L. Stivala, F. Mirabelli, P. Richelmi, S. Orrenius
- Chemistry, Medicine
- Proceedings of the National Academy of Sciences…
- 15 May 1992
The intracellular distribution of glutathione (GSH) in cultured hepatocytes has been investigated by using the compound monochlorobimane (BmCl), which interacts specifically with GSH to form a highly… Expand
Calcium‐dependent DNA fragmentation in human synovial cells exposed to cold shock
- M. Perotti, F. Toddei, +4 authors S. Orrenius
- Chemistry, Medicine
- FEBS letters
- 1990
Exposure of confluent human synovial McCoy's cells to near‐freezing temperatures followed by rewarming at 37°C resulted in endonuclease activation and cell death characteristic of a suicide process… Expand
Selective blockade of mGlu5 metabotropic glutamate receptors protects rat hepatocytes against hypoxic damage
- M. Storto, U. de Grazia, +5 authors M. Vairetti
- Biology, Medicine
- Hepatology
- 1 March 2000
Western blot analysis of protein extracts from rat liver revealed the presence of the mGlu5 receptor, one of the G‐protein–coupled receptors activated by glutamate (named “metabotropic glutamate… Expand
Evaluation of ADMA-DDAH-NOS axis in specific brain areas following nitroglycerin administration: study in an animal model of migraine
- R. Greco, A. Ferrigno, +6 authors C. Tassorelli
- Medicine
- The Journal of Headache and Pain
- 13 August 2015
BackgroundNitric oxide (NO) is known to play a key role in migraine pathogenesis, but modulation of NO synthesis has failed so far to show efficacy in migraine treatment. Asymmetric dimethylarginine… Expand
Cytoskeleton as a target in menadione‐induced oxidative stress in cultured mammalian cells. I. Biochemical and immunocytochemical features
- G. Bellomo, F. Mirabelli, M. Vairetti, F. Iosi, W. Malorni
- Biology, Medicine
- Journal of cellular physiology
- 1 April 1990
Cytoskeletal abnormalities occurring during oxidative stress generated by the metabolism of the redox cycling compound 2‐methyl‐1,4‐naphtoquinone (menadione) have been investigated in different… Expand
Correlation between the liver temperature employed during machine perfusion and reperfusion damage: Role of Ca2+
- M. Vairetti, A. Ferrigno, +7 authors U. Cillo
- Medicine
- Liver transplantation : official publication of…
- 1 April 2008
This study compares the effects of machine perfusion (MP) at different temperatures with simple cold storage. In addition, the role of Ca2+ levels in the MP medium was evaluated. For MP, rat livers… Expand
Troubleshooting and improving the mouse and rat isolated perfused liver preparation.
- A. Ferrigno, P. Richelmi, M. Vairetti
- Medicine
- Journal of pharmacological and toxicological…
- 1 March 2013
INTRODUCTION
Isolated perfused liver (IPL) model is not only widely performed in rats but is also used in mouse liver, although a detailed description of this procedure is absent. A comparison of the… Expand
Decreased apoptosis in fatty livers submitted to subnormothermic machine-perfusion respect to cold storage
- E. Boncompagni, E. Gini, +6 authors I. Freitas
- Biology, Medicine
- European journal of histochemistry : EJH
- 19 October 2011
Machine perfusion at subnormothermic temperature (20°C), MP20, was developed by Vairetti et al. and showed to afford a better preservation of fatty livers respect to traditional cold storage (CS) in… Expand
Different susceptibility of liver grafts from lean and obese Zucker rats to preservation injury.
- A. Ferrigno, F. Carlucci, +9 authors M. Vairetti
- Chemistry, Medicine
- Cryobiology
- 1 December 2009
We compared the susceptibility of liver grafts from lean and obese Zucker rats to preservation injury, using two organ-preservation techniques: conventional static preservation (SP) and machine… Expand