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- Publications
- Influence
Therapeutic antibodies: successes, limitations and hopes for the future
- P. Chames, M. V. Van Regenmortel, E. Weiss, D. Baty
- Biology, Medicine
- British journal of pharmacology
- 1 May 2009
With more than 20 molecules in clinical use, monoclonal antibodies have finally come of age as therapeutics, generating a market value of $11 billion in 2004, expected to reach $26 billion by 2010.… Expand
Isolation of viral IgY antibodies from yolks of immunized hens.
- A. Polson, M. B. von Wechmar, M. V. Van Regenmortel
- Biology, Medicine
- Immunological communications
- 1980
Antibodies were isolated from the yolks of hens that were immunized with a variety of plant viruses by the use of polyethylene glycol (PEG). A concentration of 3.5% of the polymer caused the lipids… Expand
The increased incidence of pure red cell aplasia with an Eprex formulation in uncoated rubber stopper syringes.
- K. Boven, S. Stryker, +6 authors N. Casadevall
- Medicine
- Kidney international
- 1 June 2005
BACKGROUND
The incidence of pure red cell aplasia (PRCA) in chronic kidney disease patients treated with epoetins increased substantially in 1998, was shown to be antibody mediated, and was… Expand
Towards a consensus on datasets and evaluation metrics for developing B‐cell epitope prediction tools
- J. Greenbaum, P. Andersen, +20 authors Bjoern Peters
- Computer Science, Medicine
- Journal of molecular recognition : JMR
- 1 March 2007
TLDR
Arthritogenic Monoclonal Antibodies from K/BxN Mice
- Mariana Maccioni, G. Zeder‐Lutz, +9 authors D. Mathis
- Biology, Medicine
- The Journal of experimental medicine
- 15 April 2002
Arthritis in the K/BxN mouse model is provoked by pathogenic antibodies (Abs) directed against a ubiquitously expressed protein, glucose-6-phosphate isomerase (GPI). To begin dissecting the… Expand
Synthetic peptides as antigens: pitfalls of conjugation methods.
- J. Briand, S. Muller, M. V. Van Regenmortel
- Chemistry, Medicine
- Journal of immunological methods
- 8 April 1985
Peptide-carrier conjugates were prepared using 9 different synthetic peptides, 3 carrier proteins and 4 coupling reagents. Residues of the carrier protein that were modified by different coupling… Expand
Predicting location of continuous epitopes in proteins from their primary structures.
- J. Pellequer, E. Westhof, M. V. Van Regenmortel
- Chemistry, Medicine
- Methods in enzymology
- 1991
Publisher Summary This chapter describes epitopes that are considered as “functional epitopes”—that is, portions or fragments of a protein that are able to bind to antibody in an immunoassay—and not… Expand
Correlation between the location of antigenic sites and the prediction of turns in proteins.
- J. Pellequer, E. Westhof, M. V. Van Regenmortel
- Biology, Medicine
- Immunology letters
- 1 April 1993
In the present study, we developed new turn scales based on the occurrence of amino acids at each of the four positions of a turn using a structural database comprised of 87 proteins. We found that… Expand
Use of recombinant fusion proteins and monoclonal antibodies to define linear and discontinuous antigenic sites on the dengue virus envelope glycoprotein.
- F. Mégret, J. Hugnot, +7 authors M. V. Van Regenmortel
- Biology, Medicine
- Virology
- 1 April 1992
Sixteen overlapping fragments of the dengue-2 virus envelope (E) protein, expressed as trpE-E fusion products in Escherichia coli, were used to map the epitopes defined by a panel of 20 monoclonal… Expand
Comparison of molecular and immunological typing of isolates of Rice yellow mottle virus
- D. Fargette, A. Pinel, H. Halimi, C. Brugidou, C. Fauquet, M. V. Van Regenmortel
- Biology, Medicine
- Archives of Virology
- 1 March 2002
Summary. Isolates of Rice yellow mottle virus (RYMV) were typed at the molecular level through the sequences of the open reading frame (ORF) 4 (coding for the coat protein) and ORF1 (coding for the… Expand
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