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Induction of Genes Mediating Interferon-dependent Extracellular Trap Formation during Neutrophil Differentiation*
Interferons (IFNs) are cytokines that possess potent anti-viral and immunoregulatory activities. In contrast, their potential role(s) in anti-bacterial defense and neutrophil activation mechanisms isExpand
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HLA-G protein up-regulation in primary cutaneous lymphomas is associated with interleukin-10 expression in large cell T-cell lymphomas and indolent B-cell lymphomas.
Primary cutaneous lymphomas (CLs) constitute a spectrum of diseases characterized by a clonal accumulation of lymphocytes in the skin. Most CLs display a T(h)2 cytokine profile, including expressionExpand
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Disease-independent skin recruitment and activation of plasmacytoid predendritic cells following imiquimod treatment.
BACKGROUND Imiquimod, an immune response modifier that is used topically to treat different types of skin cancer, induces the production of proinflammatory cytokines that stimulate an antitumorExpand
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Human leukocyte antigen-G and cancer immunoediting.
Immunosurveillance is an extrinsic mechanism of cancer suppression that eliminates nascent tumors. However, the selection imposed by immunosurveillance can drive tumor evolution and the emergence ofExpand
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Human leukocyte antigen G up-regulation in lung cancer associates with high-grade histology, human leukocyte antigen class I loss and interleukin-10 production.
Immune evasion in lung cancer results from both structural and functional alterations of human leukocyte antigen (HLA) class I molecules and the local release of immunosuppressive cytokines. RecentExpand
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Mechanisms underlying imiquimod-induced regression of basal cell carcinoma in vivo.
BACKGROUND Imiquimod is a local immune response modifier that has demonstrated potent antiviral and antitumor activity. It enhances innate and acquired immune responses via endogenous cytokineExpand
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HLA-G and IL-10 expression in human cancer--different stories with the same message.
Immune evasion in cancer may result from structural and functional alterations of human leukocyte antigen (HLA) class I molecules and/or local release of immunosuppressive cytokines, such asExpand
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Green tea extract reduces induction of p53 and apoptosis in UVB‐irradiated human skin independent of transcriptional controls
Abstract:  Ultraviolet (UV) irradiation plays a pivotal role in human skin carcinongenesis. Preclinically, systemically and topically applied green tea extract (GTE) has shown reduction of UV‐inducedExpand
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Spontaneous CD8 T Cell Responses against the Melanocyte Differentiation Antigen RAB38/NY-MEL-1 in Melanoma Patients1
The melanocyte differentiation Ag RAB38/NY-MEL-1 was identified by serological expression cloning (SEREX) and is expressed in the vast majority of melanoma lesions. The immunogenicity ofExpand
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Expression of melanoma‐associated antigens in melanoma cell cultures
Abstract:  The efficiency of melanoma immunotherapy appears to depend on both melanoma‐ and immune system‐specific factors. Melanoma‐specific factors include melanoma‐associated antigen (MAA)Expand
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