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- Publications
- Influence
Induction of Genes Mediating Interferon-dependent Extracellular Trap Formation during Neutrophil Differentiation*
- S. Martinelli, M. Urošević, +6 authors S. Yousefi
- Medicine, Biology
- Journal of Biological Chemistry
- 15 October 2004
Interferons (IFNs) are cytokines that possess potent anti-viral and immunoregulatory activities. In contrast, their potential role(s) in anti-bacterial defense and neutrophil activation mechanisms is… Expand
HLA-G protein up-regulation in primary cutaneous lymphomas is associated with interleukin-10 expression in large cell T-cell lymphomas and indolent B-cell lymphomas.
- M. Urošević, J. Willers, B. Mueller, W. Kempf, G. Burg, R. Dummer
- Biology, Medicine
- Blood
- 15 January 2002
Primary cutaneous lymphomas (CLs) constitute a spectrum of diseases characterized by a clonal accumulation of lymphocytes in the skin. Most CLs display a T(h)2 cytokine profile, including expression… Expand
Disease-independent skin recruitment and activation of plasmacytoid predendritic cells following imiquimod treatment.
- M. Urošević, R. Dummer, +4 authors M. Gilliet
- Medicine
- Journal of the National Cancer Institute
- 3 August 2005
BACKGROUND
Imiquimod, an immune response modifier that is used topically to treat different types of skin cancer, induces the production of proinflammatory cytokines that stimulate an antitumor… Expand
Human leukocyte antigen-G and cancer immunoediting.
- M. Urošević, R. Dummer
- Biology, Medicine
- Cancer research
- 1 February 2008
Immunosurveillance is an extrinsic mechanism of cancer suppression that eliminates nascent tumors. However, the selection imposed by immunosurveillance can drive tumor evolution and the emergence of… Expand
Human leukocyte antigen G up-regulation in lung cancer associates with high-grade histology, human leukocyte antigen class I loss and interleukin-10 production.
- M. Urošević, M. Kurrer, +6 authors A. Trojan
- Biology, Medicine
- The American journal of pathology
- 1 September 2001
Immune evasion in lung cancer results from both structural and functional alterations of human leukocyte antigen (HLA) class I molecules and the local release of immunosuppressive cytokines. Recent… Expand
Mechanisms underlying imiquimod-induced regression of basal cell carcinoma in vivo.
- M. Urošević, T. Maier, B. Benninghoff, H. Slade, G. Burg, R. Dummer
- Medicine
- Archives of dermatology
- 1 October 2003
BACKGROUND
Imiquimod is a local immune response modifier that has demonstrated potent antiviral and antitumor activity. It enhances innate and acquired immune responses via endogenous cytokine… Expand
HLA-G and IL-10 expression in human cancer--different stories with the same message.
- M. Urošević, R. Dummer
- Biology, Medicine
- Seminars in cancer biology
- 1 October 2003
Immune evasion in cancer may result from structural and functional alterations of human leukocyte antigen (HLA) class I molecules and/or local release of immunosuppressive cytokines, such as… Expand
Green tea extract reduces induction of p53 and apoptosis in UVB‐irradiated human skin independent of transcriptional controls
- C. D. Mnich, K. Hoek, +5 authors R. Dummer
- Biology, Medicine
- Experimental dermatology
- 1 January 2009
Abstract: Ultraviolet (UV) irradiation plays a pivotal role in human skin carcinongenesis. Preclinically, systemically and topically applied green tea extract (GTE) has shown reduction of UV‐induced… Expand
Spontaneous CD8 T Cell Responses against the Melanocyte Differentiation Antigen RAB38/NY-MEL-1 in Melanoma Patients1
- S. Walton, M. Gerlinger, +16 authors A. Zippelius
- Biology, Medicine
- The Journal of Immunology
- 1 December 2006
The melanocyte differentiation Ag RAB38/NY-MEL-1 was identified by serological expression cloning (SEREX) and is expressed in the vast majority of melanoma lesions. The immunogenicity of… Expand
Expression of melanoma‐associated antigens in melanoma cell cultures
- M. Urošević, B. Braun, J. Willers, G. Burg, R. Dummer
- Biology, Medicine
- Experimental dermatology
- 1 July 2005
Abstract: The efficiency of melanoma immunotherapy appears to depend on both melanoma‐ and immune system‐specific factors. Melanoma‐specific factors include melanoma‐associated antigen (MAA)… Expand