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Stressed mycobacteria use the chaperone ClpB to sequester irreversibly oxidized proteins asymmetrically within and between cells.
- Julien Vaubourgeix, G. Lin, +11 authors C. Nathan
- Biology, Medicine
- Cell host & microbe
- 11 February 2015
Mycobacterium tuberculosis (Mtb) defends itself against host immunity and chemotherapy at several levels, including the repair or degradation of irreversibly oxidized proteins (IOPs). To investigate… Expand