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Review: Oxygen and trophoblast biology--a source of controversy.
Oxygen is necessary for life yet too much or too little oxygen is toxic to cells. The oxygen tension in the maternal plasma bathing placental villi is <20 mm Hg until 10-12 weeks' gestation, risingExpand
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Placental volume and vascular flow assessed by 3D power Doppler and adverse pregnancy outcomes.
OBJECTIVE To estimate the utility of first-trimester 3D-placental volume and vascular flow indices in the prediction of adverse pregnancy outcomes. METHODS A prospective cohort study includingExpand
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Staples Compared With Subcuticular Suture for Skin Closure After Cesarean Delivery: A Systematic Review and Meta-Analysis
OBJECTIVE: To estimate whether staples or subcuticular suture closure is associated with a higher risk of wound complications when used for transverse skin incisions after cesarean delivery. DATAExpand
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Early pregnancy vaginal microbiome trends and preterm birth
Background Despite decades of attempts to link infectious agents to preterm birth, an exact causative microbe or community of microbes remains elusive. Nonculture 16S ribosomal RNA gene sequencingExpand
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Maternal Marijuana Use and Adverse Neonatal Outcomes: A Systematic Review and Meta-analysis
OBJECTIVE: To estimate whether marijuana use in pregnancy increases risks for adverse neonatal outcomes and clarify if any increased risk is attributable to marijuana use itself or to confoundingExpand
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Loop Electrosurgical Excision Procedure and Risk of Preterm Birth: A Systematic Review and Meta-analysis
OBJECTIVE: To assess whether loop electrosurgical excision procedure (LEEP) increases the risk for preterm birth before 37 weeks of gestation and clarify whether the increased risk for preterm birthExpand
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  • Open Access
Perinatal Outcomes in Women With Subchorionic Hematoma: A Systematic Review and Meta-Analysis
OBJECTIVE: To estimate the association between subchorionic hematoma and adverse perinatal outcomes. DATA SOURCES: MEDLINE, EMBASE, and the Cochrane Library. METHODS OF STUDY SELECTION: We searchedExpand
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  • Open Access
First‐trimester assessment of placenta function and the prediction of preeclampsia and intrauterine growth restriction
Preeclampsia and intrauterine growth restriction (IUGR) are major contributors to perinatal mortality and morbidity worldwide. Both are characterized by impaired trophoblastic invasion of theExpand
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First-trimester serum analytes, biophysical tests and the association with pathological morphometry in the placenta of pregnancies with preeclampsia and fetal growth restriction.
OBJECTIVE We test the hypothesis that first-trimester serum analytes, 4-D power Doppler placental vascular indices and uterine artery Doppler (UAD) predicts abnormal placental morphometry inExpand
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