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Incidence and risk factors of vascular dementia and Alzheimer's disease in a defined elderly Japanese population
Article abstract—We followed 828 nondemented residents of Hisayama Town, Kyushu, Japan, aged 65 years or older (88.3% of the elderly population) for 7 years starting in 1985 in order to determine theExpand
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Endometrial Stromal Sarcomas and Related High-grade Sarcomas: Immunohistochemical and Molecular Genetic Study of 31 Cases
Classification and terminology of non–low-grade endometrial sarcomas, which show significant nuclear atypia, have been controversial. Currently, these tumors seem to be classified all together intoExpand
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c-kit and PDGFRA Mutations in Extragastrointestinal Stromal Tumor (Gastrointestinal Stromal Tumor of the Soft Tissue)
Extragastrointestinal stromal tumor (EGIST) is a unique tumor that occurs outside the gastrointestinal tract. EGIST shows a c-kit expression and histologic appearance similar to those ofExpand
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Combined hepatocellular and cholangiocarcinoma: proposed criteria according to cytokeratin expression and analysis of clinicopathologic features.
We herein evaluated 36 cases of combined hepatocellular and cholangiocarcinoma (cHCC-CC) (including 29 surgically resected and seven autopsy cases) by the immunohistochemical methods ofExpand
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The association of death-associated protein kinase hypermethylation with early recurrence in superficial bladder cancers.
Mechanisms for bladder carcinogenesis and the development of recurrentbladder cancer remain unclear. Aberrant methylation of the 5' CpG island is thought to play an important role in the inactivationExpand
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Transcriptional repressor snail and progression of human hepatocellular carcinoma.
PURPOSE Snail protein is a suppressive transcriptional factor of E-cadherin that mediates cell-to-cell adhesion, tumor progression, and metastases. We explored the expression and function of SnailExpand
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Primary gastrointestinal lymphoma in Japan
An optimal treatment modality for patients with primary gastrointestinal lymphoma has not yet been established. This study aimed to elucidate the clinicopathologic features of this disease and theExpand
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Apparent diffusion coefficients of breast tumors: clinical application.
PURPOSE To evaluate the usefulness of apparent diffusion coefficient (ADC) for the differential diagnosis of breast tumors and to determine the relation between ADC and tumor cellularity. MATERIALSExpand
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Hepatoid adenocarcinoma of the stomach. A clinicopathologic and immunohistochemical analysis
Background. The clinicopathologic and immunohistochemical features of the primary gastric hepatoid adenocarcinomas still remain unclear.
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Cyclooxygenase 2 is a key enzyme for inflammatory cytokine‐induced angiogenesis
  • T. Kuwano, S. Nakao, +4 authors M. Ono
  • Biology, Medicine
  • FASEB journal : official publication of the…
  • 1 February 2004
Cyclooxygenasel (COX1) and COX2 mediate the rate‐limiting step in arachidonic acid me¬tabolism. Expression of COX2 mRNA and protein is often enhanced in various human cell types by inflam¬matoryExpand
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