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Ultrastructure and phylogenetic analysis of 'Candidatus Neoehrlichia mikurensis' in the family Anaplasmataceae, isolated from wild rats and found in Ixodes ovatus ticks.
A novel bacterium that infects laboratory rats was isolated from wild Rattus norvegicus rats in Japan and it was revealed that the organism represents a novel clade in the family Anaplasmataceae, which includes the Schotti variant found in Ixodes ricinus ticks in the Netherlands and the Ehrlichia-like Rattus strain found in R. norveGicus rats from China. Expand
Epizootiologic survey for Babesia microti among small wild mammals in northeastern Eurasia and a geographic diversity in the beta-tubulin gene sequences.
Findings suggest that U.S-type B. microti is widely distributed among small wild mammals in temperate zones of not only North America, but also Eurasia, whereas that Hobetsu- and Kobe-type parasites may be uniquely distributed in Japan. Expand
Molecular Survey of Babesia microti, Ehrlichia Species and Candidatus Neoehrlichia mikurensis in Wild Rodents from Shimane Prefecture, Japan
This study demonstrates the presence of several potentially important tick‐borne pathogens in Shimane Prefecture and suggests the need for further study on the causative agents of FUOs. Expand
First Case of Human Babesiosis in Korea: Detection and Characterization of a Novel Type of Babesia sp. (KO1) Similar to Ovine Babesia
The present study provides the first evidence of the presence of a hitherto unidentified, new type of Babesia parasite capable of infecting humans. Expand
Molecular evidence for the presence of new Babesia species in feral raccoons (Procyon lotor) in Hokkaido, Japan.
Detailed molecular survey for piroplasma infections of feral raccoons with normal spleen in Hokkaido, Japan using nested PCR that target broadly to 18S ribosomal RNA gene (SSU-rDNA) of all the parasites in the genus Babesia revealed that six of nine positives were found to be infected with BabesIA and the remaining three with previously unreported Sarcocystis. Expand
Human Babesiosis in Japan: Isolation ofBabesia microti-Like Parasites from an Asymptomatic Transfusion Donor and from a Rodent from an Area Where Babesiosis Is Endemic
  • Qiang Wei, M. Tsuji, +5 authors C. Ishihara
  • Biology, Medicine
  • Journal of Clinical Microbiology
  • 1 June 2001
The index case patient acquired infection by transfusion from a donor who became infected in Japan, that parasitemia in an asymptomatic carrier can persist for more than a year, and that A. speciosus serves as a reservoir of an agent of human babesiosis in Japan. Expand
Transfusion-Acquired, Autochthonous Human Babesiosis in Japan: Isolation of Babesia microti-Like Parasites with hu-RBC-SCID Mice
It is concluded that the first Japanese babesiosis case occurred due to a blood transfusion and that the etiological agent is an indigenous Japanese parasite which may be a geographical variant of B. microti. Expand
Human Babesiosis in Japan: Epizootiologic Survey of Rodent Reservoir and Isolation of New Type of Babesia microti-Like Parasite
The results suggest that a new type of B.microti-like parasite, namely, the Hobetsu type, is the major one which is prevalent among Japanese wild rodents, that A. speciosus serves as a major reservoir for both Kobe- and Hobetsu-type B. microti- like parasites, and that C. rufocanus may also be an additional reservoir on Hokkaido Island. Expand
Sequence polymorphism in the ribosomal DNA internal transcribed spacers differs among Theileria species.
The genomic region spanning the two ribosomal RNA internal transcribed spacers (ITS1 and ITS2) and the 5.8S rRNA gene-ITS2 region was cloned and sequenced from sixteen Theileria isolates and the spacers were most polymorphic in the agent of tropical theileriosis. Expand
Babesia microti-group parasites compared phylogenetically by complete sequencing of the CCTeta gene in 36 isolates.
The results have strong implications for public health, suggesting that the B. microti-group parasites are a full-fledged genus comprising, for now, four core species, i.e., U.S., Kobe, Hobetsu, and Munich species nova. Expand