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Ultraviolet irradiation induces acute changes in melanocytic nevi.
Ultraviolet (UV) light represents one of the factors that might play a role in the initiation and promotion of malignant transformation of human melanocytes. To determine the short-term effects of UVExpand
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S2k Guidelines for Cutaneous Basal Cell Carcinoma – Part 2: Treatment, Prevention and Follow‐up
Basal cell carcinoma (BCC) is the most common malignant tumor among fair‐skinned individuals, and its incidence had been steadily rising in the past decades. In order to maintain the highest qualityExpand
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Infantile digital fibromatosis. Immunohistochemical and immunoelectron microscopic studies
A typical case of infantile digital fibromatosis (IDF) was studied with antibodies raised against actin, vimentin, desmin and several species of cytokeratin. Strong reactions were observed forExpand
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S2k Guidelines for Cutaneous Basal Cell Carcinoma – Part 1: Epidemiology, Genetics and Diagnosis
Basal cell carcinoma is the most common malignant tumor among fair‐skinned individuals, and its incidence has been rising steadily in the past decades. In order to maintain the highest quality ofExpand
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One single erythemagenic UV irradiation is more effective in increasing the proliferative activity of melanocytes in melanocytic naevi compared with fractionally applied high doses
The effect of a single irradiation with UV light on the expression of Ki67 antigen, topoisomerase IIα, proliferating cell nuclear antigen (PCNA), the melanocyte activation marker HMB‐45 and proteinExpand
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Detection of Merkel Cell Polyomavirus and Human Papillomaviruses in Merkel Cell Carcinoma Combined With Squamous Cell Carcinoma in Immunocompetent European Patients
Background: About 10% of patients with Merkel cell carcinoma (MCC) suffer from an associated squamous cell carcinoma (SCC). In European patients, Merkel cell polyomavirus (MCPyV) is detectable inExpand
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MMP‐2, TIMP‐2 and MT1‐MMP are differentially expressed in lesional skin of melanocytic nevi and their expression is modulated by UVB‐light
Background:  In malignant melanoma, recent studies have demonstrated an important role of matrix‐metalloproteinase 2 (MMP‐2), its co‐activating enzyme membrane‐type matrix‐metalloproteinase 1Expand
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Verrucous-Keratotic Malignant Melanoma (VKMM)
We report a patient with a verrucous keratotic variant of melanoma visiting the policlinic of Medical Institute of Ministry of Interior (MVR-Sofia), Department of Dermatology and DermatologicExpand
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Overhydroxylation of lysyl residues is the initial step for altered collagen cross-links and fibril architecture in fibrotic skin.
In fibrotic skin of lipodermatosclerosis a substantial increase of the cross-link hydroxylysylpyridinoline is observed. Hydroxylysylpyridinoline is a typical cross-link of skeletal tissue and isExpand
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Histologic features of granulomatous skin diseases. Part 1: Non‐infectious granulomatous disorders
Granulomatous disorders affecting the skin belong to a heterogeneous group of diseases. With the exception of granulomas induced by infectious agents or foreign bodies, the etiopathogenesis ofExpand
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