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The ecology and evolution of ant association in the Lycaenidae (Lepidoptera).
TLDR
Both demographic and phylogenetic evidence indicate that ant association has shaped the evolution of obligately associated groups, and further research on phylogeny and natural history, particularly of the Neotropical fauna, will be necessary to understand the role ants have played in the Evolution of the Lycaenidae. Expand
Resistance to Antimalarial Drugs: Molecular, Pharmacologic, and Clinical Considerations
TLDR
This review provides an update of the current understanding of the molecular basis for antimalarial drug resistance and current efforts to characterize and deter resistance to new combination therapy. Expand
Acoustics, context and function of vibrational signalling in a lycaenid butterfly–ant mutualism
TLDR
Using pupal pairs in which one member was experimentally muted, pupal calls were shown to be important in ant attraction and the maintenance of an ant guard, suggesting that larval calls may beImportant in mediating ant symbioses. Expand
Plasmodium vivax Infections over 3 Years in Duffy Blood Group Negative Malians in Bandiagara, Mali.
Plasmodium vivax was thought to infect only the erythrocytes of Duffy blood group positive people. In the last decade, P. vivax has appeared throughout Africa, both in areas where Duffy positive andExpand
Stable malaria incidence despite scaling up control strategies in a malaria vaccine-testing site in Mali
TLDR
A sharp seasonality in malaria illness incidence was observed with higher clinical malaria incidence rates during the rainy season, and Parasite and anaemia point prevalence showed seasonal variation with much higher prevalence rates during rainy seasons compared to dry seasons. Expand
Population-scale Longitudinal Mapping of COVID-19 Symptoms, Behavior, and Testing
TLDR
It is shown that self-reported surveys can be used to build predictive models to identify likely COVID-19-positive individuals and highlight the utility of collecting a diverse set of symptomatic, demographic, exposure and behavioural self- reported data to fight the CO VID-19 pandemic. Expand
Spatio-temporal analysis of malaria within a transmission season in Bandiagara, Mali
TLDR
Assessment of time and space distribution of malaria disease in Bandiagara, Mali within a transmission season confirms the existence of a marked spatial heterogeneity of malaria transmission, providing support for implementation of targeted interventions. Expand
Strains used in whole organism Plasmodium falciparum vaccine trials differ in genome structure, sequence, and immunogenic potential
TLDR
Tens of thousands of variants between NF54 and the three heterologous strains both genome-wide and within regulatory and immunologically important regions, including in pre-erythrocytic antigens that may be key for sporozoite vaccine-induced protection are identified. Expand
Seroreactivity to a large panel of field-derived Plasmodium falciparum apical membrane antigen 1 and merozoite surface protein 1 variants reflects seasonal and lifetime acquired responses to malaria.
TLDR
Results help to validate diversity-covering protein microarrays as a promising tool for measuring the breadth of antibody responses to highly variant proteins, and demonstrate the potential of this new tool to help guide the development of malaria vaccines with strain-transcending efficacy. Expand
Seroreactivity to Plasmodium falciparum erythrocyte membrane protein 1 intracellular domain in malaria-exposed children and adults.
TLDR
Seroreactivity to PfEMP1 fragments was higher in adults than in children; intracellular conserved fragments were more widely recognized than were extracellular hypervariable fragments. Expand
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