M. Townsend

Publications52
h-index13
Citations402
Highly Influential Citations15
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Echinocandin pharmacodynamics: review and clinical implications.
Echinocandins have made a significant impact in the treatment of select invasive fungal infections, most notably invasive candidiasis and aspergillosis. However, treatment outcomes for such… Expand
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Incidence of Drug Interactions Identified by Clinical Pharmacists in Veterans Initiating Treatment for Chronic Hepatitis C Infection
Background: Many direct-acting antivirals (DAAs) have drug-drug interactions (DDIs) with the potential to affect efficacy and safety. Objective: To describe the incidence and severity of DDIs with… Expand
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Incidence of Severe Hepatotoxicity Related to Antiretroviral Therapy in HIV/HCV Coinfected Patients
Introduction. Hepatotoxicity is a concern in HIV/hepatitis C virus (HCV) coinfected patients due to their underlying liver disease. This study assessed the incidence of hepatotoxicity in HIV/HCV… Expand
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Tigecycline: a new glycylcycline antimicrobial
Tigecycline is a new glycyclcycline antimicrobial recently approved for use in the USA, Europe and elsewhere. While related to the tetracyclines, tigecycline overcomes many of the mechanisms… Expand
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Recent advances in the treatment of life-threatening, invasive fungal infections
Introduction: Invasive fungal infections (IFIs) pose significant morbidity and are often life-threatening to many high-risk patients. Timely diagnosis and treatment of these infections with optimal… Expand
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Trimethoprim‐Sulfamethoxazole‐Induced Hepatotoxicity in a Pediatric Patient
Due to the escalating rates of community‐acquired methicillin‐resistant Staphylococcus aureus (CA‐MRSA) infection, trimethoprim‐sulfamethoxazole (TMP‐SMX) is being used increasingly in the pediatric… Expand
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Potential role of tigecycline in the treatment of community-acquired bacterial pneumonia
Tigecycline is a member of the glycylcycline class of antimicrobials, which is structurally similar to the tetracycline class. It demonstrates potent in vitro activity against causative pathogens… Expand
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Reducing Inappropriate Antibiotic Prescribing for Adults With Acute Bronchitis in an Urgent Care Setting: A Quality Improvement Initiative
Acute bronchitis is a predominantly viral illness and, according to clinical practice guidelines, should not be treated with antibiotics. Despite clear guidelines, acute bronchitis continues to be… Expand
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Relationship between Vancomycin Area Under the Concentration-Time Curve (AUC) and Nephrotoxicity in Adults
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Overview of treatment options for invasive fungal infections.
The introduction of several new antifungals has significantly expanded both prophylaxis and treatment options for invasive fungal infections (IFIs). Relative to amphotericin B deoxycholate,… Expand
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