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Activation of R-Ras by Ras-Guanine Nucleotide-releasing Factor*
TLDR
Findings raise the possibility that R-Ras is activated by Ras-GRF in brain and testis, and by C3G in other tissues, respectively, according to the guanine nucleotide-releasing activities of Ras- GRF, mSos, and C3g. Expand
Role of oxidative stress in germ cell apoptosis induced by di(2-ethylhexyl)phthalate.
TLDR
Results indicate that oxidative stress elicited by MEHP principally injured mitochondrial function and induced the release of cytochrome c, thereby inducing apoptosis of spermatocytes and causing atrophy of the testis. Expand
Izumoring: a novel and complete strategy for bioproduction of rare sugars.
TLDR
Bioproduction strategies for all rare sugars are illustrated using ring form structures given the name Izumoring. Expand
Cancer susceptibility and embryonic lethality in Mob1a/1b double-mutant mice.
TLDR
It is shown that intact Mob1a or Mob1b is essential for murine embryogenesis and that loss of the remaining WT Mob1 allele inMob1a(Δ/Δ)1b(tr/+) or Mob2a(tr/tr) mice results in tumor development, and MOB1A and Mob1B have overlapping functions in skin homeostasis and exert their roles as tumor suppressors by regulating downstream elements of the Hippo pathway. Expand
Induction of indoleamine 2,3-dioxygenase in mouse lung during virus infection.
TLDR
Indoleamine 2,3-dioxygenase activity in the supernatant fraction of mouse lung homogenate increased approximately 120-fold after infection with PR8 influenza virus, and appeared to be closely related to the infiltrations of mononuclear and lymphocytic cells. Expand
Molecular cloning of the novel human G protein-coupled receptor (GPCR) gene mapped on chromosome 9.
TLDR
A novel human GPCR gene was cloned by PCR with degenerate primers designed from cannabinoid type 1 receptor sequences and a full-length clone was isolated by screening of a human genomic DNA library and showed that a 2.8 kb transcript of EDG-3 is abundantly expressed in the heart followed by placenta, kidney and liver. Expand
Annexin A2 expression and phosphorylation are up-regulated in hepatocellular carcinoma.
TLDR
The data suggest that overexpression and tyrosine phosphorylation of ANXA2 play important roles in the malignant transformation process leading to HCC and are related to the histological grade of HCC. Expand
Conformational changes induced by binding of divalent cations to calregulin.
TLDR
Of 12 cations tested, only Zn2+ and Ca2+ produced changes in calregulin intrinsic fluorescence, and none of these metal ions could inhibit or mimic the Zn 2+-induced blue shift in ANS emission maximum. Expand
The role of artificial and natural sweeteners in reducing the consumption of table sugar: A narrative review.
TLDR
Identifying natural sweeteners that have favorable effects on body weight and metabolism may help achieving the current recommendations of restricting simple sugar consumption. Expand
Study on the Postprandial Blood Glucose Suppression Effect of D-Psicose in Borderline Diabetes and the Safety of Long-Term Ingestion by Normal Human Subjects
TLDR
The results suggest that D-psicose had an effect to suppress the postprandial blood glucose elevation mainly in borderline diabetes cases. Expand
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