M. Thun

Publications574
h-index152
Citations156,385
Highly Influential Citations4,419
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Lung cancer, cardiopulmonary mortality, and long-term exposure to fine particulate air pollution.
TLDR
Fine particulate and sulfur oxide--related pollution were associated with all-cause, lung cancer, and cardiopulmonary mortality and long-term exposure to combustion-related fine particulate air pollution is an important environmental risk factor for cardiopULmonary and lung cancer mortality.
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Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults.
TLDR
Current patterns of overweight and obesity in the United States could account for 14 percent of all deaths from cancer in men and 20 percent of those in women, and increased body weight was associated with increased death rates for all cancers combined and for cancers at multiple specific sites.
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Particulate air pollution as a predictor of mortality in a prospective study of U.S. adults.
  • C. A. Pope, M. Thun, C. Heath
  • Environmental Science
    American journal of respiratory and critical care…
  • 1 March 1995
TLDR
Increased mortality is associated with sulfate and fine particulate air pollution at levels commonly found in U.S. cities, although the increase in risk is not attributable to tobacco smoking, although other unmeasured correlates of pollution cannot be excluded with certainty.
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Body-mass index and mortality in a prospective cohort of U.S. adults.
TLDR
The risk of death from all causes, cardiovascular disease, cancer, or other diseases increases throughout the range of moderate and severe overweight for both men and women in all age groups.
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Cancer Statistics, 2008
TLDR
This report examines cancer incidence, mortality, and survival by site, sex, race/ethnicity, education, geographic area, and calendar year, as well as the proportionate contribution of selected sites to the overall trends.
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Extended follow-up and spatial analysis of the American Cancer Society study linking particulate air pollution and mortality.
We conducted an extended follow-up and spatial analysis of the American Cancer Society (ACS) Cancer Prevention Study II (CPS-II) cohort in order to further examine associations between long-term…
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Cancer Disparities by Race/Ethnicity and Socioeconomic Status
TLDR
Differences in cancer incidence, mortality, and survival in relation to race/ethnicity, and census data on poverty in the county or census tract of residence are highlighted.
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A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer
TLDR
Four SNPs in intron 2 of FGFR2 (which encodes a receptor tyrosine kinase and is amplified or overexpressed in some breast cancers) that were highly associated with breast cancer were identified and confirmed in 1,776 affected individuals and 2,072 controls from three additional studies.
View on Nature
Long-term ozone exposure and mortality.
TLDR
In this large study, it was not able to detect an effect of ozone on the risk of death from cardiovascular causes when the concentration of PM(2.5) was taken into account, but a significant increase in the risk from respiratory causes was demonstrated in association with an increase in ozone concentration.
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Cardiovascular Mortality and Long-Term Exposure to Particulate Air Pollution: Epidemiological Evidence of General Pathophysiological Pathways of Disease
TLDR
Fine particulate air pollution is a risk factor for cause-specific cardiovascular disease mortality via mechanisms that likely include pulmonary and systemic inflammation, accelerated atherosclerosis, and altered cardiac autonomic function.
View on Wolters Kluwer
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