• Publications
  • Influence
Rapid and sequential movement of individual chromosomal loci to specific subcellular locations during bacterial DNA replication.
The chromosomal origin and terminus of replication are precisely localized in bacterial cells. We examined the cellular position of 112 individual loci that are dispersed over the circularExpand
  • 403
  • 42
  • PDF
A comprehensive set of plasmids for vanillate- and xylose-inducible gene expression in Caulobacter crescentus
Caulobacter crescentus is widely used as a powerful model system for the study of prokaryotic cell biology and development. Analysis of this organism is complicated by a limited selection of toolsExpand
  • 283
  • 28
  • PDF
FtsN‐like proteins are conserved components of the cell division machinery in proteobacteria
In bacteria, cytokinesis is mediated by a ring‐shaped multiprotein complex, called divisome. While some of its components are widely conserved, others are restricted to certain bacterial lineages.Expand
  • 78
  • 12
Chromosome organization and segregation in bacteria.
In the recent years, considerable advances have been made towards understanding the structure and function of the bacterial chromosome. A number of different factors appear to cooperate in condensingExpand
  • 111
  • 11
The dynamic interplay between a cell fate determinant and a lysozyme homolog drives the asymmetric division cycle of Caulobacter crescentus.
Caulobacter crescentus divides asymmetrically into a swarmer cell and a stalked cell, a process that is governed by the imbalance in phosphorylated levels of the DivK cell fate determinant in the twoExpand
  • 120
  • 8
DipM, a new factor required for peptidoglycan remodelling during cell division in Caulobacter crescentus
In bacteria, cytokinesis is dependent on lytic enzymes that facilitate remodelling of the cell wall during constriction. In this work, we identify a thus far uncharacterized periplasmic protein,Expand
  • 76
  • 7
  • PDF
Localized Dimerization and Nucleoid Binding Drive Gradient Formation by the Bacterial Cell Division Inhibitor MipZ
Summary Protein gradients play a central role in the spatial organization of cells, but the mechanisms of their formation are incompletely understood. This study analyzes the determinants responsibleExpand
  • 88
  • 6
  • PDF
Getting organized — how bacterial cells move proteins and DNA
In recent years, the subcellular organization of prokaryotic cells has become a focal point of interest in microbiology. Bacteria have evolved several different mechanisms to target proteinExpand
  • 121
  • 5
The bacterial nucleoid: A highly organized and dynamic structure
Recent advances in bacterial cell biology have revealed unanticipated structural and functional complexity, reminiscent of eukaryotic cells. Particular progress has been made in understanding theExpand
  • 132
  • 5