TranslatorX: multiple alignment of nucleotide sequences guided by amino acid translations
- F. Abascal, R. Zardoya, M. Telford
- BiologyNucleic Acids Res.
- 30 April 2010
TranslatorX is presented, a web server designed to align protein-coding nucleotide sequences based on their corresponding amino acid translations, with a rich output, including Jalview-powered graphical visualization of the alignments, codon-based alignments coloured according to the corresponding amino acids, measures of compositional bias and first, second and third codon position specific alignments.
Acoelomorph flatworms are deuterostomes related to Xenoturbella
- H. Philippe, H. Brinkmann, M. Telford
- BiologyNature
- 10 February 2011
This phylogeny makes sense of the shared characteristics of Xenoturbellida and Acoelomorpha, and implies the loss of various deuterostome characters in the Xenobiology including coelomic cavities, through gut and gill slits.
Deuterostome phylogeny reveals monophyletic chordates and the new phylum Xenoturbellida
- Sarah J. Bourlat, Thorhildur Juliusdottir, M. Telford
- BiologyNature
- 2 November 2006
To study the relationships among all deuterostome groups, an alignment of more than 35,000 homologous amino acids is assembled, including new data from a hemichordate, starfish and Xenoturbella and it is concluded that chordates are monophyletic.
MicroRNAs and phylogenomics resolve the relationships of Tardigrada and suggest that velvet worms are the sister group of Arthropoda
- Lahcen Campbell, Omar Rota-Stabelli, D. Pisani
- BiologyProceedings of the National Academy of Sciences
- 6 September 2011
The study confirms the monophyly of the legged ecdysozoans, shows that past support for a Tardigrada + Nematoda group was due to long-branch attraction, and suggests that the velvet worms are the sister group to the arthropods.
Consideration of RNA secondary structure significantly improves likelihood-based estimates of phylogeny: examples from the bilateria.
- M. Telford, M. Wise, Vivek Gowri-Shankar
- BiologyMolecular biology and evolution
- 1 April 2005
A novel permutation approach is used to demonstrate the significant superiority of models of sequence evolution that allow stem and loop regions to evolve according to separate models and it is shown that 16-state models that take base pairing of stems into account are significantly better than simpler, 4-state, single-nucleotide models.
Expression of homeobox genes shows chelicerate arthropods retain their deutocerebral segment.
- M. Telford, R. H. Thomas
- BiologyProceedings of the National Academy of Sciences…
- 1 September 1998
Embrailed expression, which has been used to demonstrate the presence of segments in insects, fails to demonstrate a reduced deutocerebral segment and further inferences are made concerning the evolution of heads and Hox genes in arthropods.
Hox genes and the phylogeny of the arthropods
- C. E. Cook, M. Smith, M. Telford, Alberto Bastianello, M. Akam
- BiologyCurrent Biology
- 15 May 2001
Xenoturbella is a deuterostome that eats molluscs
- Sarah J. Bourlat, C. Nielsen, A. Lockyer, D. Littlewood, M. Telford
- Biology, Environmental ScienceNature
- 21 August 2003
It is shown that the samples in these studies were contaminated by bivalve embryos eaten by Xenoturbella and that XenOTurbella is in fact a deuterostome related to hemichordates and echinoderms.
Uncertainty in the Timing of Origin of Animals and the Limits of Precision in Molecular Timescales
- M. dos Reis, Y. Thawornwattana, K. Angelis, M. Telford, P. Donoghue, Ziheng Yang
- Biology, Environmental ScienceCurrent Biology
- 16 November 2015
A congruent solution to arthropod phylogeny: phylogenomics, microRNAs and morphology support monophyletic Mandibulata
- Omar Rota-Stabelli, Lahcen Campbell, M. Telford
- BiologyProceedings of the Royal Society B: Biological…
- 22 January 2011
The phylogenomic analyses strongly support Mandibulata, and show that Myriochelata is a tree-reconstruction artefact caused by saturation and long-branch attraction, and provide strong support for the inclusion of pycnogonids in a monophyletic Chelicerata, a paraphyletic Cycloneuralia, and a common origin of Arthropoda.
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