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An evaluation of the male reproductive toxicity of cathinone.
(-)-Cathinone is the major psychoactive component of khat plant (Catha edulis Forssk.). Khat has been shown to produce reproductive toxicity in human beings and experimental animals. However, theExpand
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N-acetylcysteine attenuates cyclosporin-induced nephrotoxicity in rats.
BACKGROUND Cyclosporin (CsA) has played an important role in the improvement of solid-organ transplant patients and graft survival. However, nephrotoxicity due to CsA remains an important clinicalExpand
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Pentoxifylline ameliorates lithium-pilocarpine induced status epilepticus in young rats
The neuroprotective effects of pentoxifylline (PTX) against lithium-pilocarpine (Li-Pc)-induced status epilepticus (SE) in young rats are described. Animals treated with PTX (0, 20, 40, and 60 mg/kg)Expand
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Gastric antisecretory and antiulcer effects of simvastatin in rats
Background and Aim:  Recently, statins have appeared to have additional benefits beyond their lipid lowering effects, which has led to the interest in the use of this class of drugs outside the realmExpand
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Evaluation of mastic, a crude drug obtained from Pistacia lentiscus for gastric and duodenal anti-ulcer activity.
The effect of mastic, a concrete resinous exudate obtained from the stem of the tree Pistacia lentiscus, has been studied on experimentally-induced gastric and duodenal ulcers in rats. Mastic at anExpand
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Toxicity studies on six plants used in the traditional Arab system of medicine
Toxicity studies were done on six plants used in the traditional Arab system of medicine, namely: Aloe vera, Ammi majus, Areca catachu, Citrullus colocynthis, Cuminum cyminum and ZizyphusExpand
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Evaluation of turmeric (Curcuma longa) for gastric and duodenal antiulcer activity in rats.
An ethanol extract of turmeric was studied in rats for its ability to inhibit gastric secretion and to protect gastroduodenal mucosa against the injuries caused by pyloric ligation,Expand
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Anti-inflammatory activity of Teucrium polium.
Teucrium polium is widely used by the folk-medicine practitioners in Saudi Arabia for the treatment of inflammations, rheumatism, diabetes and ulcers. Scientific reports are lacking to confirm theseExpand
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Neuroprotective effect of nicotine against 3-nitropropionic acid (3-NP)-induced experimental Huntington's disease in rats
Nicotinic acetylcholine receptors (nAChRs) are regarded as potential therapeutic targets to control various neurodegenerative diseases. Owing to the relevance of cholinergic neurotransmission in theExpand
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Gastroprotective activity of ginger zingiber officinale rosc., in albino rats.
The cytoprotective and gastric anti-ulcer studies of ginger have been carried out in albino rats. Cytodestruction was produced by 80% ethanol, 0.6M HC1, 0.2M NaOH and 25% NaCl. Whereas gastric ulcersExpand
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