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Intravenous erythropoietin in patients with ST-segment elevation myocardial infarction: REVEAL: a randomized controlled trial.
CONTEXT Acute ST-segment elevation myocardial infarction (STEMI) is a leading cause of morbidity and mortality. In experimental models of MI, erythropoietin reduces infarct size and improves leftExpand
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Cardioprotection by Intermittent Fasting in Rats
Background— Intermittent fasting (IF), a dietary regimen in which food is available only every other day, increases the life span and reduces the incidence of age-associated diseases in rodents. WeExpand
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Metabolic costs of mounting an antigen-stimulated immune response in adult and aged C57BL/6J mice.
Animals must balance their energy budget despite seasonal changes in both energy availability and physiological expenditures. Immunity, in addition to growth, thermoregulation, and cellularExpand
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Erythropoietin reduces myocardial infarction and left ventricular functional decline after coronary artery ligation in rats
Erythropoietin (EPO), well known for its role in stimulation of erythropoiesis, has recently been shown to have a dramatic neuroprotective effect in animal models of cerebral ischemia, mechanicalExpand
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Metabolic costs of mounting an antigen-stimulated immune response in adult and aged C57BL/6J mice.
Animals must balance their energy budget despite seasonal changes in both energy availability and physiological expenditures. Immunity, in addition to growth, thermoregulation, and cellularExpand
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Cardioprotective and Survival Benefits of Long-Term Combined Therapy with β2 Adrenoreceptor (AR) Agonist and β1 AR Blocker in Dilated Cardiomyopathy Postmyocardial Infarction
We have reported therapeutic effectiveness of pharmacological stimulation of β2 adrenoreceptors (ARs) to attenuate the cardiac remodeling and myocardial infarction (MI) expansion in a rat model ofExpand
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Oxygen consumption in adult and aged C57BL/6J mice during acute treadmill exercise of different intensity
Submaximal and maximal oxygen consumption was determined in untrained adult and aged male C57BL/6J mice during treadmill running. Each of 12-month-old (ADULT) and 24-month-old (AGED) male mice wasExpand
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Beneficial Effects of Chronic Pharmacological Manipulation of &bgr;-Adrenoreceptor Subtype Signaling in Rodent Dilated Ischemic Cardiomyopathy
Background—Studies in isolated cardiac myocytes have demonstrated that signaling via specific &bgr;1-adrenergic receptor subtypes (&bgr;1ARs) promotes but that signaling via &bgr;2ARs protects fromExpand
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SRT1720 improves survival and healthspan of obese mice
Sirt1 is an NAD+-dependent deacetylase that extends lifespan in lower organisms and improves metabolism and delays the onset of age-related diseases in mammals. Here we show that SRT1720, a syntheticExpand
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Cardioprotective effect of intermittent fasting is associated with an elevation of adiponectin levels in rats.
It has been reported that dietary energy restriction, including intermittent fasting (IF), can protect heart and brain cells against injury and improve functional outcome in animal models ofExpand
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