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Long-term treatment of generalised myasthenia gravis with FK506 (tacrolimus)
Efficacy and safety of long term use of FK506 (2–4.5 mg/day) for a maximum of two years were evaluated in 12 patients with generalised myasthenia gravis (MG). At the end of the study, eight patientsExpand
  • 64
  • 4
Randomised, double-blind, placebo-controlled study of tacrolimus in myasthenia gravis
Objectives To evaluate the ability of tacrolimus to reduce the corticosteroid dose in patients with myasthenia gravis (MG) and the drug's safety in a double-blind, placebo-controlled, parallel groupExpand
  • 72
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Autoantibodies against TRPC3 and ryanodine receptor in myasthenia gravis
  • M. Takamori
  • Medicine, Biology
  • Journal of Neuroimmunology
  • 30 August 2008
The transient receptor potential canonical type-3 (TRPC3, receptor- and store-operated Ca(2+) influx channel) participates in skeletal muscle contraction; its functional interactions with ryanodineExpand
  • 22
  • 3
Patterns and severity of neuromuscular transmission failure in seronegative myasthenia gravis
Objectives: To compare the clinical and electrophysiological features of myasthenia gravis (MG) patients with (seropositive) or without (seronegative) antibodies to acetylcholine receptor. ToExpand
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Pure akinesia manifested neuroleptic malignant syndrome: a clinical variant of progressive supranuclear palsy
Abstract An autopsy case of pure akinesia (PA) is reported. The patient manifested l-dopa-unresponsive akinesia without accompanying rigidity, tremor, eye movement disorder or dementia from the ageExpand
  • 19
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Shy-Drager syndrome. Effect of fludrocortisone and L-threo-3,4-dihydroxyphenylserine on the blood pressure and regional cerebral blood flow.
In nine cases of Shy-Drager syndrome, the changes in blood pressure and cerebral blood flow on sitting up from a supine position were studied. The influence of fludrocortisone, a syntheticExpand
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[A patient with amnesic syndrome with defective route finding due to left posterior cerebral artery territory infarction].
We report a right-handed 67-year-old woman with an infarction in the left posterior cerebral artery territory presenting amnesic syndrome, right homonymous hemianopsia, pure alexia, color anomia, andExpand
  • 6
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Myasthenogenic significance of synthetic α-subunit peptide 183–200 of Torpedo californica and human acetylcholine receptor
Synthetic peptides of the Torpedo californica and human acetylcholine receptor alpha-subunit, Gly183-Asp200, were studied. Both peptides bound alpha-bungarotoxin to a significant extent, andExpand
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The Eaton-Lambert syndrome and autoimmune disorders.
Abstract The Eaton-Lambert syndrome is a myasthenic disorder often associated with small cell carcinoma of the lung. We describe a patient with hypothyroidism and pernicious anemia in addition toExpand
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Spontaneous thymoma rat as a model for myasthenic weakness caused by anti-ryanodine receptor antibodies.
The mechanism of muscle weakness in myasthenia gravis and its possible relation to antibodies that are directed against the ryanodine receptor (RyR) were studied by the use of the spontaneous thymomaExpand
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