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Beyond the comparator model: A multifactorial two-step account of agency
TLDR
A sharp distinction is drawn between a non-conceptual level of feeling of agency and a conceptual level of judgement of agency, which is able to provide a unified account for the sense of agency for both actions and thoughts. Expand
Targeted next generation sequencing as a diagnostic tool in epileptic disorders
Purpose:  Epilepsies have a highly heterogeneous background with a strong genetic contribution. The variety of unspecific and overlapping syndromic and nonsyndromic phenotypes often hampers a clearExpand
Ataxia with oculomotor apraxia type 2: clinical, biological and genotype/phenotype correlation study of a cohort of 90 patients.
Ataxia with oculomotor apraxia type 2 (AOA2) is an autosomal recessive disease due to mutations in the senataxin gene, causing progressive cerebellar ataxia with peripheral neuropathy, cerebellarExpand
The Cerebellum Updates Predictions about the Visual Consequences of One's Behavior
TLDR
Patients with cerebellar lesions and their matched controls were equally able to detect experimental modifications of visual feedback about their pointing movements, but in interleaved trials without actual feedback, patients did no longer account for this feedback rotation--neither perceptually nor with respect to motor performance. Expand
I move, therefore I am: A new theoretical framework to investigate agency and ownership
TLDR
A new systematic account of two of its main features, thesense of agency and the sense of ownership, is provided, demonstrating that although both features appear as phenomenally uniform, they each are complex crossmodal phenomena of largely heterogeneous functional and (self-)representational levels. Expand
A Pan-European Study of the C9orf72 Repeat Associated with FTLD: Geographic Prevalence, Genomic Instability, and Intermediate Repeats
TLDR
In vitro reporter gene expression studies demonstrated significantly decreased transcriptional activity of C9orf72 with increasing number of normal repeat units, indicating that intermediate repeats might act as predisposing alleles and in favor of the loss‐of‐function disease mechanism. Expand
S100B is increased in Parkinson’s disease and ablation protects against MPTP-induced toxicity through the RAGE and TNF-α pathway
TLDR
A role of S100B in the pathophysiology of Parkinson’s disease is demonstrated and Targeting S 100B may emerge as a potential treatment strategy in this disorder. Expand
Intensive coordinative training improves motor performance in degenerative cerebellar disease
TLDR
In patients with cerebellar ataxia, coordinative training improves motor performance and reduces ataxIA symptoms, enabling them to achieve personally meaningful goals in everyday life. Expand
The experience of agency: an interplay between prediction and postdiction
TLDR
The framework of optimal cue integration offers a promising approach that directly stimulates a wide range of experimentally testable hypotheses on agency processing in different subject groups. Expand
The tumour suppressor gene WWOX is mutated in autosomal recessive cerebellar ataxia with epilepsy and mental retardation.
TLDR
It is demonstrated that proline 47 is a key amino acid essential for maintaining the WWOX protein fully functional, with its mutation into a threonine resulting in a loss of peptide interaction for the first WW domain. Expand
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