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- Publications
- Influence
El Escorial revisited: Revised criteria for the diagnosis of amyotrophic lateral sclerosis
- B. Brooks, R. Miller, M. Swash, T. Munsat
- Medicine
- Amyotrophic lateral sclerosis and other motor…
- 1 January 2000
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder involving primarily motor neurons in the cerebral cortex, brainstem and spinal cord. The variability in clinical… Expand
Electrodiagnostic criteria for diagnosis of ALS
- M. Carvalho, R. Dengler, A. Eisen, J. England, M. Swash
- Medicine
- Clinical Neurophysiology
- 1 March 2008
A consensus meeting was held to determine the best use and interpretation of electrophysiological data in the diagnosis of ALS. The utility of needle EMG and nerve conduction studies was affirmed. It… Expand
Changes in motor unit synchronization following central nervous lesions in man.
- S. Farmer, M. Swash, D. Ingram, J. Stephens
- Medicine, Psychology
- The Journal of physiology
- 1 April 1993
1. Single motor unit spike trains have been recorded during voluntary isometric contraction of the affected intrinsic hand muscles of patients with unilateral central nervous lesions. These have been… Expand
Multifocal motor neuropathy
- V. Chaudhry, M. Swash
- Medicine
- Neurology
- 22 August 2006
Recognition of new clinical phenotypes requires knowledge and clinical experience together with a new insight, often provided by an unexpected test result. Sometimes, as in multifocal motor… Expand
INJURY TO INNERVATION OF PELVIC FLOOR SPHINCTER MUSCULATURE IN CHILDBIRTH
- S. Snooks, M. Swash, M. Setchell, M. M. Henry
- Medicine
- The Lancet
- 8 September 1984
71 women delivered at St Bartholomew's Hospital, London, were studied by electrophysiological tests of the innervation of the external anal sphincter muscle and by manometry. The investigations were… Expand
Slowed conduction in the pudendal nerves in idiopathic (neurogenic) faecal incontinence
We have studied 30 patients with idiopathic (neurogenic) faecal incontinence using anorectal manometry and concentric needle and single fibre electromyographic methods. We have measured the terminal… Expand
Hippocampal and neocortical ubiquitin-immunoreactive inclusions in amyotrophic lateral sclerosis with dementia
- G. Wightman, V. E. Anderson, J. Martín, M. Swash, P. Leigh
- Medicine
- Neuroscience Letters
- 25 May 1992
Amyotrophic lateral sclerosis (ALS) patients with dementia were found to have ubiquitin-immunoreactive (IR) inclusions in the dentate granule cells of the hippocampus. These inclusions were also… Expand
Effect of vaginal delivery on the pelvic floor: A 5‐year follow‐up
- S. Snooks, M. Swash, S. Mathers, M. M. Henry
- Medicine
- The British journal of surgery
- 1 December 1990
We have studied the pelvic floor musculature and its innervation in 14 of 24 (58 per cent) multiparous women who had been recruited into a study of the effect of childbirth on the pelvic floor as… Expand
Ubiquitin-immunoreactive intraneuronal inclusions in amyotrophic lateral sclerosis. Morphology, distribution, and specificity.
- P. Leigh, H. Whitwell, +6 authors B. Anderton
- Biology, Medicine
- Brain : a journal of neurology
- 1 April 1991
Antibodies to ubiquitin have been used to search for evidence of abnormal protein degradation in amyotrophic lateral sclerosis--motor neuron disease (ALS). Anterior horn cell ubiquitin-immunoreactive… Expand
Molecular mechanisms and phenotypic variation in RYR1-related congenital myopathies.
- Haiyan Zhou, H. Jungbluth, +19 authors F. Muntoni
- Medicine, Biology
- Brain : a journal of neurology
- 1 August 2007
Dominant mutations in the skeletal muscle ryanodine receptor (RYR1) gene are well-recognized causes of both malignant hyperthermia susceptibility (MHS) and central core disease (CCD). More recently,… Expand