• Publications
  • Influence
Effectiveness of antipsychotic drugs in patients with chronic schizophrenia.
TLDR
Olanzapine was the most effective in terms of the rates of discontinuation, and the efficacy of the conventional antipsychotic agent perphenazine appeared similar to that of quetiapine, risperidone, and ziprasidone. Expand
Sex and depression in the National Comorbidity Survey. I: Lifetime prevalence, chronicity and recurrence.
TLDR
Age of onset analysis shows that this sex difference begins in early adolescence and persists through the mid-50s and means that the higher prevalence of 12-month depression among women than men is largely due to women having a higher risk of first onset. Expand
The prevalence and distribution of major depression in a national community sample: the National Comorbidity Survey.
TLDR
A greater burden of major depression in community-dwelling persons than has been estimated from previous community samples is suggested and the risk factor profile showed significant differences between persons with pure and combined major depression. Expand
A national study of violent behavior in persons with schizophrenia.
TLDR
To examine the prevalence and correlates of violence among schizophrenia patients living in the community by developing multivariable statistical models to assess the net effects of psychotic symptoms and other risk factors for minor and serious violence, a large number of patients diagnosed as having schizophrenia were enrolled. Expand
Comorbidity of DSM-III-R major depressive disorder in the general population: results from the US National Comorbidity Survey.
TLDR
The analysis shows that most cases of lifetime MDD are secondary, in the sense that they occur in people with a prior history of another DSM-III-R disorder, which is more persistent and severe than pure or primary MDD. Expand
Prevalence of HIV, hepatitis B, and hepatitis C in people with severe mental illness.
TLDR
Elevated rates of HIV, HBV, and HCV were found among individuals with severe mental illness, of particular concern are the high rates of HCV infection, which are frequently undetected. Expand
Prevalence, correlates, and course of minor depression and major depression in the National Comorbidity Survey.
TLDR
It is argued that minor depression is a variant of depressive disorder that should be considered seriously both as a target for preventive intervention and for treatment. Expand
Effectiveness of clozapine versus olanzapine, quetiapine, and risperidone in patients with chronic schizophrenia who did not respond to prior atypical antipsychotic treatment.
TLDR
For patients with schizophrenia who prospectively failed to improve with an atypical antipsychotic, clozapine was more effective than switching to another newer atypicals antipsychotics. Expand
Sex and depression in the National Comorbidity Survey. II: Cohort effects.
TLDR
A cohort difference in 12-month MDE is found, with older women much more likely than older men to have recurrent episodes, and this sex difference in recurrence plays an important part in the elevated 12- month prevalence of depression among women compared to men in the 45-54 age range. Expand
The National Institute of Mental Health Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) project: schizophrenia trial design and protocol development.
TLDR
The CATIE schizophrenia trial blends features of efficacy studies and large, simple trials to create a pragmatic trial that will provide extensive information about antipsychotic drug effectiveness over at least 18 months. Expand
...
1
2
3
4
5
...