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Deficiency in p57Kip2 expression induces preeclampsia-like symptoms in mice.
p57Kip2, a potent inhibitor of several cyclin/cyclin dependent kinase complexes (CDK ), is a paternally imprinted gene in both humans and mice, and here we show that pregnant mice which areExpand
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  • Open Access
Immunohistochemical Study of Annexin V Expression in Placentae of Preeclampsia
We investigated the clinical significance of annexin V in the placentae with preeclampsia and found: (1) annexin V was detected on trophoblasts in the placentae and the staining intensity of annexinExpand
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Increased Cell‐surface Urokinase in Advanced Ovarian Cancer
Urokinase‐type plasminogen activator (uPA), uPA receptors, and cathepsin B were quantitatcd by using an immunological method, enzyme‐linked immunosorbent assay, and amidolytic activity assays in 15Expand
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Time spatial labeling inversion pulse magnetic resonance angiography in pregnancy with adenomyosis
Time spatial labeling inversion pulse (Time‐SLIP) is a non‐contrast magnetic resonance angiography (MRA) technique. No cases in which this technique was used during pregnancy have been reported. WeExpand
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Overexpression of the ERK/MAP kinases in oral squamous cell carcinoma.
Mitogen-activated protein kinase (MAPK) is a serine-threonine kinase that is activated by various extracellular stimuli. Extracellular signal-regulated kinases (ERK1 and ERK2), an MAPK subfamily, areExpand
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Phosphatidylserine/phosphatidylcholine microvesicles can induce preeclampsia-like changes in pregnant mice.
We established a phosphatidylserine (PS)/phosphatidylcholine (PC) microvesicles-induced preeclampsia-like model in mice. PS/PC were prepared by mixing 80% PC and 20% PS, and suspended in 0.05 MExpand
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Measurement of placental oxygenation by transabdominal near-infrared spectroscopy.
The uteroplacental circulation in the placenta can have a major impact on the fetus. Near infrared spectroscopy (NIRS) is the noninvasive method of measuring changes in blood volumes and oxygenExpand
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Exogenous vascular endothelial growth factor can induce preeclampsia-like symptoms in pregnant mice.
It is reported that expression of vascular endothelial growth factor (VEGF) in trophoblasts increases in cases with preeclampsia. Recently, we demonstrated that the lack of cyclin-dependent kinaseExpand
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Chorangiosis and placental oxygenation
Chorangiosis is a vascular hyperplasia in the terminal chorionic villi, usually diagnosed histologically using the criteria of Altshuler. Its true etiology has not been fully identified, butExpand
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