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The crystal structure of human mitochondrial 3-ketoacyl-CoA thiolase (T1): insight into the reaction mechanism of its thiolase and thioesterase activities.
TLDR
Crystal structures of human mitochondrial 3-ketoacyl-CoA thiolase (hT1) in the apo form and in complex with CoA confirm the tetrameric quaternary structure and it is shown that T1 has significant biosynthetic thioesterase activity, which is predicted to be of physiological importance.
Ambient air pollutants in upper Silesia: partial chemical composition and biological activity.
TLDR
Mutagenicity tested on Salmonella strains showed seasonal variation with distinctly higher values in winter, and Environmentally exposed humans showed a higher level of PAH-DNA adducts in WBC than the control population from rural area.
A molecular epidemiology study in women from Upper Silesia, Poland.
The present report is a follow-up to our previous molecular epidemiology studies on DNA damage in residents of the industrial region of Upper Silesia. The study was designed to focus on environmental
Determination of heterocyclic aromatic amines (HAs) content in samples of household-prepared meat dishes.
TLDR
To achieve this, HAs fractions were derivatized to pentafluoropropionic acid (PFPA) amide derivatives, and the calculated values of theoretically daily human exposure to five determined HAs were in the range of 0.2-7.7 microg per day per person.
Acyl-CoA thioesterase 9 (ACOT9) in mouse may provide a novel link between fatty acid and amino acid metabolism in mitochondria
TLDR
ACOT9 is the major mitochondrial ACOT hydrolyzing saturated C2-C20-CoA in mouse brown adipose tissue and kidney mitochondria, and its activity is strongly regulated by NADH and CoA, suggesting that mitochondrial metabolic state regulates the function of ACOT9.
Synthesis of ultramarine from synthetic molecular sieves
Abstract Methods of ultramarine production using synthetic zeothetic zeolites as substrates have been developed. In contrast to the conventional method the emission of sulfur oxides is almost
Clean-up procedures for the analysis of heterocyclic aromatic amines (aminoazaarenes) from heat-treated meat samples.
TLDR
The results of the studies showed that a solid-phase extraction procedure using diatomaceous earth, propylsulphonic acid and octadecylsilane columns was the quickest and simplest one.
The use of cationic liposomes DC-CHOL/DOPE and DDAB/DOPE for direct transfer of Escherichia coli cytosine deaminase gene into growing melanoma tumors.
An attempt was made to use simple cationic liposomes DC-Chol/DOPE and DDAB/DOPE (DC-Chol is 3 beta (N(N',N-dimethylaminoethane) carbamoyl) cholesterol, DDAB is dimethyldioctadecyl ammonium bromide
Benzo(a)pyrene-albumin adducts in humans exposed to polycyclic aromatic hydrocarbons in an industrial area of Poland.
TLDR
A multiple regression analysis of the measured concentrations of BPDE-albuminAdducts for all the groups, during both seasons, indicates that occupational exposures do not contribute significantly to the formation of adducts.
Effect of the spectral range of a UV lamp on the production of cyclobutane pyrimidine dimers in human skin in situ
TLDR
The effect of different wave bands of UV light on the production of DNA damage in human skin in situ was studied with a broadbandUV‐B lamp TL‐12 and a narrowband UV‐B Lamp TL‐01.
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