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Genetic history of an archaic hominin group from Denisova Cave in Siberia
TLDR
A tooth found in Denisova Cave carries a mitochondrial genome highly similar to that of the finger bone, further indicating that Denisovans have an evolutionary history distinct from Neanderthals and modern humans. Expand
African populations and the evolution of human mitochondrial DNA.
TLDR
The African origin hypothesis of human mtDNA evolution is supported by two statistical tests and two hypervariable segments of mtDNA were sequenced from 189 people of diverse geographic origin, including 121 native Africans. Expand
Mitochondrial DNA and human evolution
TLDR
All these mitochondrial DMAs stem from one woman who is postulated to have lived about 200,000 years ago, probably in Africa, implying that each area was colonised repeatedly. Expand
Neandertal DNA Sequences and the Origin of Modern Humans
TLDR
Neandertals went extinct without contributing mtDNA to modern humans, according to sequence comparisons with human mtDNA sequences, as well as phylogenetic analyses, which show that the Neandertal sequence falls outside the variation of modern humans. Expand
Mitochondrial DNA and two perspectives on evolutionary genetics
This essay reviews comparative studies of animal mitochondrial DNA (mtDNA), with emphasis on findings made and ideas developed at Berkeley. It argues that such studies are bringing together twoExpand
Mitochondrial DNA and human evolution
  • M. Stoneking
  • Biology, Medicine
  • Journal of bioenergetics and biomembranes
  • 1 June 1994
TLDR
A new method of analyzing mtDNA data is described that suggests that all human populations underwent a dramatic expansion some 40,000 years ago, possibly in association with revolutionary advances in human behavior, as well as an important implication of population expansions for mtDNA disease studies. Expand
A New Approach for Using Genome Scans to Detect Recent Positive Selection in the Human Genome
TLDR
A novel approach was developed for genomic survey of recent local selective sweeps, especially aimed at those nearly or recently completed, and a new procedure was developed that indicates that certain portions of the genome clearly depart from neutrality. Expand
The Genetic Structure of Ancient Human Populations
TLDR
A new method of analyzing mtDNA sequences is used that is based on a theory of how mismatch distributions should preserve a record of population expansions and separations in the remote past. Expand
Alu insertion polymorphisms and human evolution: evidence for a larger population size in Africa.
TLDR
The results support the African origin of modern humans in that an earlier expansion of the ancestors of African populations is indicated. Expand
Characteristics and frequency of germline mutations at microsatellite loci from the human Y chromosome, as revealed by direct observation in father/son pairs.
TLDR
The data indicate that the general mutational mechanism of microsatellites is independent of recombination, and mutation rates and characteristics of human Y-chromosomal microsatellite loci are consistent with those of autosomal microSatellites. Expand
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