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Liver transplant-associated graft-versus-host disease
Closely matched human leukocyte antigen recipients, those older than 65 years, and recipients with donors more than 40 years younger were at higher risk for GVHD, and future approaches should focus on prevention. Expand
Update on treatment recommendations from the Third International Workshop on Waldenstrom's macroglobulinemia.
A consensus panel charged with providing treatment recommendations for WM updated its recommendations on both frontline and salvage therapies, finding that single-agent alkylator, nucleoside analog, or standard-dose rituximab therapy were deemed to be reasonable treatment for WM patients. Expand
Dangerous small B-cell clones.
The detection of a monoclonal immunoglobulin in serum or urine usually raises concerns about the size of the underlying B-cell-derived clone and possible systemic effects caused by its expansion.Expand
Response assessment in Waldenström macroglobulinaemia: update from the VIth International Workshop
This report represents a further update of the consensus panel criteria for the assessment of clinical response in patients with Waldenström macroglobulinaemia and a number of key changes are proposed but challenges do however remain. Expand
Prognostic markers and criteria to initiate therapy in Waldenstrom's macroglobulinemia: consensus panel recommendations from the Second International Workshop on Waldenstrom's Macroglobulinemia.
The consensus panel agreed that initiation of therapy was appropriate for patients with constitutional symptoms such as recurrent fever, night sweats, fatigue due to anemia, or weight loss and called for studies on the application of prognostic markers in WM. Expand
Evidence-based focused review of management of hyperviscosity syndrome.
Examination demonstrates mild generalized lymphadenopathy and a palpable spleen tip and the fundi show marked retinal vein engorgement with “sausaging” in patient 1. Expand
Update on recommendations for assessing response from the Third International Workshop on Waldenstrom's Macroglobulinemia.
The criteria have been updated to include minor response and stable disease categories and recognize that delayed responses after treatment with nucleoside analogues and biologic agents and the time point for assessing response in patients with WM should be considered so as to not miss or miscategorize a response. Expand
Radioimmunoassay of creatine kinase-B isoenzyme in human sera: results in patients with acute myocardial infarction.
Radioimmunoassay measurement of CPK-B isoenzyme appears to be a useful and sensitive test for the detection of acute myocardial infarcts in patients. Expand
Hematologic aspects of liver transplantation for Budd-Chiari syndrome with special reference to myeloproliferative disorders1
Antiplatelet therapy that consists of hydroxyurea and aspirin is a safe and effective alternative to anticoagulation to prevent recurrent thrombosis in MPD patients with BCS after liver transplantation. Expand
Peripheral neuropathies in Waldenström’s macroglobulinaemia
Peripheral nerve symptoms and signs occur more frequently in patients with WM than controls, involve sensory modalities, and are often associated with gait disorders. Expand