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Deficient cerebellar long-term depression and impaired motor learning in mGluR1 mutant mice
Exposure to perfluorooctane sulfonate during pregnancy in rat and mouse. II: postnatal evaluation.
- C. Lau, Julie R Thibodeaux, Lisa A. Stevenson
- Biology, MedicineToxicological sciences : an official journal of…
- 1 August 2003
It is indicated that in utero exposure to PFOS severely compromised postnatal survival of neonatal rats and mice, and caused delays in growth and development that were accompanied by hypothyroxinemia in the surviving rat pups.
Behavioral stress impairs long-term potentiation in rodent hippocampus.
Multiple memory systems, development and conditioning
- M. Stanton
- Psychology, BiologyBehavioural Brain Research
- 1 June 2000
Effects of Early Hippocampal Lesions on Trace, Delay, and Long-Delay Eyeblink Conditioning in Developing Rats
The results of two experiments indicated that hippocampal lesions impaired trace eyeblink conditioning more than either type of delay conditioning, suggesting that during ontogeny hippocampal maturation may be more important for the short-term memory component than for the long-ISI component of trace eyeblinks conditioning.
Impaired eyeblink conditioning in children with fetal alcohol syndrome.
- S. Jacobson, M. Stanton, J. Jacobson
- Medicine, PsychologyAlcoholism, clinical and experimental research
- 1 February 2008
Successful EBC in a microcephalic group supports the inference that the EBC deficit is specific to prenatal alcohol exposure and a potential biomarker for diagnosis of exposed children lacking the distinctive FAS dysmorphology.
Effects of dose and period of neonatal alcohol exposure on the context preexposure facilitation effect.
- N. J. Murawski, M. Stanton
- Psychology, BiologyAlcoholism, clinical and experimental research
- 1 June 2011
This is the first demonstration of dose-related impairment on a hippocampus-dependent task produced by neonatal alcohol exposure in the rat and it is shown that the context preexposure facilitation effect (CPFE) is a more sensitive behavioral task that can be used to elucidate developmental alcohol-induced deficits over a range of alcohol doses that are more relevant to human exposure levels.
Maternal deprivation potentiates pituitary-adrenal stress responses in infant rats.
Findings add to a growing body of literature that supports the concept of maternal regulation of infant physiology by indicating that suppression of the pituitary-adrenal system is modulated by maternal variables during the preweaning period in the rat.
Eyeblink conditioning in the developing rat.
Long-Evans rat pups, 17-18 or 24 days of age, were trained with an eyeblink conditioning procedure that was used previously with adult rats, and it was established that this effect is associative and can be modulated by motivational state.
Ontogeny of delay versus trace eyeblink conditioning in the rat.
It appears that the relative deficits in the emergence of trace eyeblink conditioning during development reflect difficulty in forming associations over long ISIs rather than the short-term memory demands of the trace conditioning paradigm.