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Broviac catheter sepsis: the natural history of an iatrogenic infection.
Between January 1982 and December 1983, 335 Broviac catheters placed in 270 infants and children were prospectively evaluated. The average duration of catheter life was 99.7 days, yielding a total… Expand
Differential sensitivity of two dopaminergic structures in rat brain to haloperidol and to clozapine.
- S. Wilk, E. Watson, M. Stanley
- Chemistry, Medicine
- The Journal of pharmacology and experimental…
- 1 November 1975
The mechanisms underlying the dissociation of the extrapyramidal and antipsychotic properties of haloperidol as compared to clozapine were explored by studying the effects of these drugs on dopamine… Expand
Striatal DOPAC elevation predicts antipsychotic efficacy of metoclopramide.
Abstract Antipsychotic drugs are known to elevate levels of 3,4-dihydroxyphenylacetic acid (DOPAC) in rat striatum in a characteristic fashion. We have found that the two benzamide derivatives… Expand
Clozapine concentrations in brain regions: relationship to dopamine metabolite increase.
Levels of clozapine in rat striatum and tuberculum olfactorium were quantitated by a gas chromatographic technique. The relationship of the increase in 3,4-dihydroxyphenylacetic acid (DOPAC) in these… Expand
D‐ AND L‐STEREOISOMERS OF ALLYLGLYCINE: CONVULSIVE ACTION AND INHIBITION OF BRAIN L‐GLUTAMATE DECARBOXYLASE
DL‐Allylglycine was resolved into the L‐ and D‐stereoisomers using hog kidney acylase. Both isomers were active as convulsants after administration to mice. The dose of D‐allylglycine required to… Expand
Interaction of drug effects with testing procedures in the measurement of catalepsy
Abstract Rats were tested for haloperidol-induced catalepsy, using the method of c ostall and Naylor (1974a, b), Costall , Naylor and Olley (1972), Costall and Olley (1971a, b). Naylor and Olley… Expand
The effect of antipsychotic drugs and their clinically inactive analogs on dopamine metabolism.
Changes in dopamine metabolite levels in the rat striatum and tuberculum olfactorium, following the administration of three non-antipsychotic butyrophenones (AL-499, AHR-1900 and U-25,927) and a… Expand
Perlapine and dopamine metabolism: prediction of antipsychotic efficacy.
A model for the prediction of antipsychotic efficacy based on the dose-dependent increase in levels of 3,4-dihydroxyphenylacetic acid (DOPAC) in the striatum and tuberculum olfactorium of the rat is… Expand
A pseudo-simulation of Shor's quantum factoring algorithm
This paper presents a computer program, written in Maple, that allows a user to simulate certain aspects of Shor's quantum factoring algorithm on a desktop or laptop computer. The program does not… Expand
Oak Seedling Establishment by Artificial Regeneration on California Rangelands1
Blue oak (Quercus douglasii H. & A.) and valley oak (Q. lobata Née) seedling establishment on California rangelands is poor in many locations. Research on artificial regeneration is documenting that… Expand