Skip to search formSkip to main contentSkip to account menu
The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands
TLDR
The IUPHAR/BPS Guide to PHARMACOLOGY (GtoPdb) database provides expert-curated molecular interactions between successful and potential drugs and their targets in the human genome, and provides an expanded substrate for the biennially published compendium, the Concise Guide topharmacology.
View PDF
The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands
TLDR
The International Union of Basic and Clinical Pharmacology/British Pharmacological Society (IUPHAR/BPS) Guide to PHARMACOLOGY is a new open access resource providing pharmacological, chemical, genetic, functional and pathophysiological data on the targets of approved and experimental drugs.
View PDF
Overview of Nomenclature of Nuclear Receptors
TLDR
The characterization of nuclear receptors and their associated proteins and the ligands that interact with them will remain a challenge to pharmacologists.
View on Publisher
The Concise Guide to Pharmacology 2013/14: G Protein-Coupled Receptors
The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of the key properties of over 2000 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug…
View on Wiley
Functional Selectivity and Classical Concepts of Quantitative Pharmacology
TLDR
Besides the heuristically interesting nature of functional selectivity, there is a clear impact on drug discovery, because this mechanism raises the possibility of selecting or designing novel ligands that differentially activate only a subset of functions of a single receptor, thereby optimizing therapeutic action.
View on Publisher
The IUPHAR/BPS Guide to PHARMACOLOGY in 2018: updates and expansion to encompass the new guide to IMMUNOPHARMACOLOGY
TLDR
This update describes content expansion, new features and interoperability improvements introduced in the 10 releases since August 2015, and introduces the newly funded project for the Guide to IMMUNOPHARMACOLOGY (GtoImmuPdb, www.guidetoimmunopharmacology.org).
View PDF
A nomenclature for ligand-gated ion channels
View on Elsevier
Cognitive dysfunction in psychiatric disorders: characteristics, causes and the quest for improved therapy
TLDR
This article critically discusses the challenges and opportunities for improving cognition in individuals suffering from psychiatric disorders, highlighting the needs to characterize the cellular and cerebral circuits underpinning cognitive function and identify more effective treatments.
View on Nature
International Union of Pharmacology Committee on Receptor Nomenclature and Drug Classification. XXXVIII. Update on Terms and Symbols in Quantitative Pharmacology
The recommendations that follow have been updated from the proposals of a Technical Subcommittee set up by the International Union of Pharmacology Committee on Receptor Nomenclature and Drug…
View on Publisher
The Concise Guide to Pharmacology 2013/14: Ion Channels
The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of the key properties of over 2000 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug…
View on Wiley
...
...
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License