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Large-scale Isolation of Highly Pure “Untouched” Regulatory T Cells in a GMP Environment for Adoptive Cell Therapy
Adoptive cell therapy is an emerging treatment strategy for a number of serious diseases. Regulatory T (Treg) cells represent 1 cell type of particular interest for therapy of inflammatory… Expand
Expansion of Umbilical Cord Blood with IGFBP2 in MSC Co-CultureSystem Ã¢ÂÂ Modest but Long-term Engraftment of Donor Cells
Background: Ex vivo expansion of umbilical cord blood (UCB) hematopoietic stem and progenitor cells (HSPCs) could reduce transplant related mortality by enabling faster donor cell engraftment. Our… Expand
Chemotherapy-induced cytotoxicity and genotoxicity to the bone marrow microenvironment
The bone marrow (BM) microenvironment is largely com- prised of mesenchymal stromal cells (MSCs) and is vital in supporting haematopoiesis. Limited studies have indicated that the BM microenvironment… Expand