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  • Influence
Typhoid fever: pathogenesis and immunologic control.
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Pathogenesis of Escherichia coli diarrhea.
Abstract Two Escherichia coli strains isolated in Vietnam from American soldiers with diarrhea and acute "colitis" were examined for virulence in both in vitro and in vivo experimental models. Thei...
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Pathogenesis of Shigella dysenteriae 1 (Shiga) dysentery.
Myron M. Levine, Herbert L. DuPont, Samuel B. Formal, Richard B. Hornick, Akio Takeuchi, Eugene J. Gangarosa, Merrill J. Snyder, and Joseph P. Libonati From the Shigella Vaccine Development Program,Expand
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Evaluation of a UDP-glucose-4-epimeraseless mutant of Salmonella typhi as a liver oral vaccine.
A mutant (Ty21a) of Salmonella typhi, which lacks the enzyme uridine 5'-diphosphate-glucose-4-epimerase, was evaluated in volunteers for use as a live attenuated oral typhoid vaccine. Five to eightExpand
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Response of man to infection with Vibrio cholerae. I. Clinical, serologic, and bacteriologic responses to a known inoculum.
The spectrum of illness and the immunologic response produced by cholera in volunteers were studied. The strains of Vibrio cholerae used were classical Inaba 569B and classical Ogawa 395. An oralExpand
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Immunity in shigellosis. I. Response of man to attenuated strains of Shigella.
Four attenuated strains of Shigella flexneri 2a have been tested for stability and safety as vaccines in man. One strain, a Shigella-Escherichia coli hybrid, was virulent for man in doses of 108Expand
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The response of man to virulent Shigella flexneri 2a.
In the United States, epidemic shigellosis has been a particularly important problem in confined groups such as the military, institutions for the mentally retarded, and Indian reservations. It is inExpand
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The Broad Street pump revisited: response of volunteers to ingested cholera vibrios.
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Immunity in shigellosis. II. Protection induced by oral live vaccine or primary infection.
Two attenuated strains of Shigella flexneri 2a, a Shigella-E. coli hybrid, and a streptomycin-dependent mutant, were safely given to adult male volunteers. When vaccinated individuals ingestedExpand
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Serodiagnosis of Rocky Mountain spotted fever: comparison of IgM and IgG enzyme-linked immunosorbent assays and indirect fluorescent antibody test.
To characterize IgM and IgG antibody responses in Rocky Mountain spotted fever (RMSF), a microtiter enzyme-linked immunosorbent assay (ELISA) using density gradient-purified Rickettsia rickettsii asExpand
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