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Epidemiology and clinical features of Mycoplasma pneumoniae infection in children.
Mycoplasma pneumoniae (MP) is, considered to affect rarely children less than 5 yrs of age. This study was performed to describe the epidemiology and the clinical features of MP lower respiratory… Expand
Risk factors for severe RSV-induced lower respiratory tract infection over four consecutive epidemics
Variability in severity among different respiratory syncytial virus (RSV) seasons may influence hospital admission rates for RSV-induced lower respiratory tract infection (LRTI) in young children.… Expand
Correlations between exhaled nitric oxide levels, blood eosinophilia, and airway obstruction reversibility in childhood asthma are detectable only in atopic individuals
The aim of this study was to compare in atopic and nonatopic asthmatic children correlations between two inflammation parameters, i.e., blood eosinophilia and exhaled nitric oxide (FENO), and… Expand
Epithelial cells and fibroblasts: structural repair and remodelling in the airways.
- O. Sacco, M. Silvestri, F. Sabatini, R. Sale, A. Defilippi, G. Rossi
- Paediatric respiratory reviews
Extensive lesions and changes in the architecture of the airway walls are commonly described in patients with respiratory infections, asthma, chronic bronchitis and interstitial lung diseases.… Expand
Risk factors for bronchiolitis hospitalization during the first year of life in a multicenter Italian birth cohort
BackgroundRespiratory Syncytial Virus (RSV) is one of the main causes of respiratory infections during the first year of life. Very premature infants may contract more severe diseases and ‘late… Expand
Bronchoalveolar lavage and esophageal pH monitoring data in children with “difficult to treat” respiratory symptoms
- O. Sacco, B. Fregonese, M. Silvestri, F. Sabatini, G. Mattioli, G. Rossi
- Pediatric pulmonology
- 1 October 2000
Gastroesophageal reflux (GER) may be associated with chronic or recurrent asthma‐like symptoms secondary to bronchoconstrictor reflexes and/or inhalation of gastric content. The presence of… Expand
Total and allergen‐specific IgE levels in serum reflect blood eosinophilia and fractional exhaled nitric oxide concentrations but not pulmonary functions in allergic asthmatic children sensitized to…
- O. Sacco, R. Sale, +5 authors G. Rossi
- Pediatric allergy and immunology : official…
- 1 December 2003
Although elevated levels of serum immunoglobulin E (IgE) are considered the hallmark of atopic diseases, their clinical value in evaluating subjects with allergic disorders is under debate. To… Expand
Maternal milk protects infants against bronchiolitis during the first year of life. Results from an Italian cohort of newborns.
OBJECTIVE Bronchiolitis is one of the primary causes of hospitalization in infancy. We evaluated the effect of breastfeeding on the occurrence of hospitalization for bronchiolitis in the first year… Expand
Orally exhaled nitric oxide levels are related to the degree of blood eosinophilia in atopic children with mild-intermittent asthma.
- M. Silvestri, D. Spallarossa, V. Frangova Yourukova, E. Battistini, B. Fregonese, G. Rossi
- The European respiratory journal
- 1 February 1999
Increased levels of nitric oxide have been found in expired air of patients with asthma, and these are thought to be related to the airway inflammatory events that characterize this disorder. Since,… Expand
Salmeterol Enhances the Inhibitory Activity of Dexamethasone on Allergen-Induced Blood Mononuclear Cell Activation
The possibility that salmeterol could interfere with the inhibitory effect of glucocorticosteroids on allergen-induced activation of leukocytes was assessed in cultures of human blood mononuclear… Expand