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Opioid Prescriptions for Chronic Pain and Overdose
BACKGROUND Long-term opioid therapy for chronic noncancer pain is becoming increasingly common in community practice. Concomitant with this change in practice, rates of fatal opioid overdose haveExpand
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Effect of early versus deferred antiretroviral therapy for HIV on survival.
BACKGROUND The optimal time for the initiation of antiretroviral therapy for asymptomatic patients with human immunodeficiency virus (HIV) infection is uncertain. METHODS We conducted two parallelExpand
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Closing the Gap: Increases in Life Expectancy among Treated HIV-Positive Individuals in the United States and Canada
Background Combination antiretroviral therapy (ART) has significantly increased survival among HIV-positive adults in the United States (U.S.) and Canada, but gains in life expectancy for this regionExpand
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Natural history and possible reactivation of human papillomavirus in human immunodeficiency virus-positive women.
BACKGROUND Little is known in human immunodeficiency virus (HIV)-positive women about how the combination of plasma HIV RNA level and CD4+ T-cell count is associated with the natural history of humanExpand
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Trends in long‐term opioid therapy for chronic non‐cancer pain
To report trends and characteristics of long‐term opioid use for non‐cancer pain.
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HIV Infection, Immunodeficiency, Viral Replication, and the Risk of Cancer
Background: Few studies have compared cancer risk between HIV-infected individuals and a demographically similar HIV-uninfected internal comparison group, adjusting for cancer risk factors. Methods:Expand
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Risk of anal cancer in HIV-infected and HIV-uninfected individuals in North America.
BACKGROUND Anal cancer is one of the most common cancers affecting individuals infected with human immunodeficiency virus (HIV), although few have evaluated rates separately for men who have sex withExpand
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Condyloma in Pregnancy Is Strongly Predictive of Juvenile‐Onset Recurrent Respiratory Papillomatosis
OBJECTIVE To assess the risk of juvenile-onset recurrent respiratory papillomatosis conferred by a maternal history of genital warts in pregnancy, and to identify additional cofactors such as theExpand
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De Facto Long-term Opioid Therapy for Noncancer Pain
ObjectivesThis paper describes characteristics of opioid use episodes for noncancer pain and defines thresholds for de facto long-term opioid therapy. MethodsCONSORT (CONsortium to Study Opioid RisksExpand
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Effects of Depression and Selective Serotonin Reuptake Inhibitor Use on Adherence to Highly Active Antiretroviral Therapy and on Clinical Outcomes in HIV-Infected Patients
Objectives:To determine the impact of depression on highly active antiretroviral therapy (HAART) adherence and clinical measures and investigate if selective serotonin reuptake inhibitors (SSRIs)Expand
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