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Is a “vanishing tumor” always a lymphoma?
TLDR
Primary CNS lymphoma (PCNL) was found in only half of the patients with a regressing cerebral mass lesion and in patients showing a complete resolution of the enhancing lesion the probability of finding a PCNL is smaller and survival is longer. Expand
Mutations in SDHD are the major determinants of the clinical characteristics of Dutch head and neck paraganglioma patients
TLDR
Evaluated SDH mutations, family history and phenotypes of patients with HNPGL in the Netherlands found that mutations in genes encoding subunits of succinate dehydrogenase (SDH) are associated with head and neck paragangliomas. Expand
Normal life expectancy for paraganglioma patients: a 50-year-old cohort revisited.
TLDR
Although surgery had more complications in the studied era than today and the death of five patients with carotid body tumors caused immediate excess mortality, the survival of the followed cohort was not significantly reduced if compared with the general population. Expand
The Dutch founder mutation SDHD.D92Y shows a reduced penetrance for the development of paragangliomas in a large multigenerational family
TLDR
The family-based study described here emphasizes the importance of the identification and inclusion of clinically unaffected mutation carriers in all estimates of penetrance and warrants a ‘wait and scan’ policy for asymptomatic paragangliomas, combined with biochemical screening for catecholamine excess in SDHD-linked patients. Expand
Paediatric hypopharyngeal perforation: child abuse until proved otherwise?
TLDR
A review of the available literature on paediatric hypopharyngeal perforation, excluding iatrogenic and external trauma mechanisms of injury suggests that non-accidental injury is by far the most common aetiology. Expand
[Tolerance and contrast density in intravenous cholangiography and cholecystography using a new contrast medium (author's transl)].
TLDR
The tolerance and diagnostic usefulness of the new intravenous bile contrast medium Endomirabil were subjected to clinical radiological testing and it is impression that it has a lower side effect quota than the other contrast media used so far. Expand
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