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Hypoxia induces differentiation of pulmonary artery adventitial fibroblasts into myofibroblasts.
TLDR
It is found that hypoxia significantly upregulates alpha-SMA protein levels in bovine pulmonary artery adventitial fibroblasts, and this increase in alpha- SMA level occurs through Galphai- and JNK-dependent signaling pathways.
New records of Lophoproctus coecus Pocock, 1894 (Diplopoda, Polyxenida, Lophoproctidae) extend the range of the genus Lophoproctus
  • M. Short
  • Biology, Environmental Science
    ZooKeys
  • 30 June 2015
TLDR
The geographic distribution of the genus Lophoproctus Pocock, 1894 has greatly expanded with new records of the species and the reassignment of a number of millipedes formerly identified as Lophoctus lucidus, found to be the sole representative of the family Lophopsinidae in collections examined from Crimea and the Caucasian region.
Epiphytes on Nothofagus cunninghamii and Eucalyptus regnans in a Victorian cool temperate rainforest
This study investigated the epiphytic communities on Myrtle Beech Nothofagus cunninghamii (Hook.) Oerst. and Mountain Ash Eucalyptus regnans F.Muell. trees in a pocket of Cool Temperate Rainforest in
Characteristics of selenazolidine prodrugs of selenocysteine: toxicity and glutathione peroxidase induction in V79 cells.
TLDR
2-unsubstituted compound, selenazolidine-4(R)-carboxylic acid (L-SCA), and the 2-oxo- and 2-methyl analogues possessing D-stereochemistry (D-OSCA and D-MSCA, respectively) were synthesized and chemically characterized, which indicates the provision of biologically available selenium.
Protein kinase Czeta attenuates hypoxia-induced proliferation of fibroblasts by regulating MAP kinase phosphatase-1 expression.
TLDR
Hypoxia activates PKCzeta, which acts as a terminator of ERK1/2 activation through the regulation of downstream target, MKP-1 expression and thus serves to limit hypoxia-induced proliferation of fibroblasts.
Selenazolidines as novel organoselenium delivery agents.
Sequence Tolerance of the Phage λ PRM Promoter: Implications for Evolution of Gene Regulatory Circuitry
TLDR
The λ circuitry is bistable—that is, lambda can exist in either of two stable epigenetic states, the lytic state and the lysogenic state, and whether one of these cis-acting sites, the PRM promoter, could tolerate substantial genetic changes and still allow relatively normal behavior of the intact circuitry is addressed.
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