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New loci associated with kidney function and chronic kidney disease
Chronic kidney disease (CKD) is a significant public health problem, and recent genetic studies have identified common CKD susceptibility variants. The CKDGen consortium performed a meta-analysis ofExpand
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Renal impairment and outcomes in heart failure: systematic review and meta-analysis.
OBJECTIVES We estimated the prevalence of renal impairment in heart failure (HF) patients and the magnitude of associated mortality risk using a systematic review of published studies. BACKGROUNDExpand
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Multiple loci associated with indices of renal function and chronic kidney disease
Chronic kidney disease (CKD) has a heritable component and is an important global public health problem because of its high prevalence and morbidity. We conducted genome-wide association studiesExpand
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Markers of inflammation, coagulation, and renal function are elevated in adults with HIV infection.
BACKGROUND Human immunodeficiency virus (HIV) replication and immune activation may increase inflammation and coagulation biomarkers. Limited data exist comparing such biomarkers in persons with andExpand
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Association of tenofovir exposure with kidney disease risk in HIV infection
Objective:Despite widespread HAART use, HIV disease remains associated with increased risk of kidney disease. Whether tenofovir use is associated with higher risk of kidney disease is controversial.Expand
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Prevalence, clinical characteristics, and mortality among patients with myocardial infarction presenting without chest pain.
CONTEXT Although chest pain is widely considered a key symptom in the diagnosis of myocardial infarction (MI), not all patients with MI present with chest pain. The extent to which this phenomenonExpand
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Racial differences in the progression from chronic renal insufficiency to end-stage renal disease in the United States.
Black Americans experience a disproportionate burden of ESRD compared with whites. Whether this is caused by the increased prevalence of chronic renal insufficiency (CRI) among blacks or by theirExpand
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Long-term risk of mortality and other adverse outcomes after acute kidney injury: a systematic review and meta-analysis.
BACKGROUND Acute kidney injury (AKI) is common in hospitalized patients. The impact of AKI on long-term outcomes is controversial. STUDY DESIGN Systematic review and meta-analysis. SETTING &Expand
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The Associations of Fibroblast Growth Factor 23 and Uncarboxylated Matrix Gla Protein With Mortality in Coronary Artery Disease: The Heart and Soul Study
BACKGROUND Fibroblast growth factor 23 (FGF23), uncarboxylated matrix Gla protein (ucMGP), and fetuin-A are regulators of mineral metabolism and inhibitors of vascular calcification. WhetherExpand
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