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Intraclonal diversity of fibrosarcoma cells for the production of macrophage colony-stimulating factor and granulocyte colony-stimulating factor.

• Naomi Sakai, Manabu Kubota, M. Shikita, Masako Yokota, Kumi Ando
• Journal of cellular physiology
• 1987

A new cell line was established from fibrosarcoma that had spontaneously developed in a mouse. The cells were maintained growing in culture for two years and constantly produced both macrophage… (More)

An unusual case of 'uncompetitive activation' by ascorbic acid: purification and kinetic properties of a myrosinase from Raphanus sativus seedlings.

• M. Shikita, Jed W Fahey, Todd Rabkin Golden, Walter David Holtzclaw, Paul Talalay
• The Biochemical journal
• 1999

Myrosinase (thioglucoside glucohydrolase; EC 3.2.3.1) is a plant enzyme that hydrolyses glucosinolates, principally to isothiocyanates. Myrosinase was purified to homogeneity in good yield from… (More)

The stoichiometry of the conversion of cholesterol and hydroxycholesterols to pregnenolone (3beta-hydroxypregn-5-en-20-one) catalysed by adrenal cytochrome P-450.

• M. Shikita, P. F. Hall
• Proceedings of the National Academy of Sciences…
• 1974

The stoichiometry of the side-chain cleavage of cholesterol (cholest-5-en-3beta-ol), 20alpha-hydroxycholesterol (cholest-5-ene-3beta,20alpha-diol), and 20alpha,22-dihydroxycholesterol… (More)

Specificity of radioprotective and cytotoxic effects of cysteamine in HeLa S3 cells: generation of peroxide as the mechanism of paradoxical toxicity.

• Yoshinari Takagi, M. Shikita, Toyozo Terasima, Shinjiro Akaboshi
• Radiation research
• 1974

Cytochrome P-450 from bovine adrenocortical mitochondria: an enzyme for the side chain cleavage of cholesterol. I. Purification and properties.

• M. Shikita, P. F. Hall
• The Journal of biological chemistry
• 1973

One cytochrome P-450 has been purified from bovine adrenocortical mitochondria to near homogeneity. The enzyme catalyzes the conversion of cholesterol and 20~ hydroxycholesterol to pregnenolone (side… (More)

Effects of recombinant human granulocyte colony-stimulating factor on the hematologic recovery and survival of irradiated mice.

• Satoshi Tanikawa, Mitsuhiko Nose, Yoshiyasu Aoki, Kenji Tsuneoka, M. Shikita, Nobuo Nara
• Blood
• 1990

We studied the effects of intraperitoneal injections of recombinant human granulocyte colony-stimulating factor (rhG-CSF) according to various administration schedules on the recovery of spleen… (More)

Preparation of highly purified 3 alpha- and 3 beta-hydroxysteroid dehydrogenases from Pseudomonas sp.

• M. Shikita, Paul Talalay
• Analytical biochemistry
• 1979

Production of macrophage colony-stimulating factor by adult murine parenchymal liver cells (hepatocytes).

• Taku Tsukui, Keiji Kikuchi, +7 authors Goro Asano
• Journal of leukocyte biology
• 1992

The activity of macrophage colony-stimulating factor (M-CSF) was found in the culture supernatant of mouse parenchymal liver cell fractions in a bone marrow colony-forming assay. The activity of an… (More)

Radioprotection of mice by a single subcutaneous injection of heat-killed Lactobacillus casei after irradiation.

• Koji Nomoto, Teruo Yokokura, Kenji Tsuneoka, M. Shikita
• Radiation research
• 1991

Treatment of whole-body gamma-irradiated mice with a preparation of Lactobacillus casei (LC 9018) immediately after irradiation caused a sustained increase in serum colony-stimulating activity which… (More)

Characterization of factors stimulating differentiation of mouse myeloid leukemia cells from a Yoshida sarcoma cell line cultured in serum-free medium.

• Motoo Hozumi, Toshiaki Umezawa, Keizo Takenaga, Takatoshi Ohno, M. Shikita, Isao Yamane
• Cancer research
• 1979

A clone, YS-T22, of cells from Yoshida sarcoma cell line, YSSF-212T, grown in "serum-free" culture medium produced factors stimulating differentiation of mouse myeloid leukemia cells (M1) to… (More)

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