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Seven naphtho-γ-pyrones from the marine-derived fungus Alternaria alternata: structure elucidation and biological properties
- M. Shaaban, K. Shaaban, M. Abdel-Aziz
- ChemistryOrganic and medicinal chemistry letters
- 29 February 2012
Eight bioactive pyrone derivatives were identified from the culture of Alternaria alternata strain D2006, isolated from the marine soft coral Denderonephthya hemprichi, which was selected as its…
Essramycin: A First Triazolopyrimidine Antibiotic Isolated from Nature†
- M. El-Gendy, M. Shaaban, K. Shaaban, A. El-Bondkly, H. Laatsch
- Chemistry, BiologyThe Journal of Antibiotics
- 1 March 2008
A novel triazolopyrimidine antibiotic was obtained from the culture broth of the marine Streptomyces sp.
Mansouramycins A-D, cytotoxic isoquinolinequinones from a marine streptomycete.
Cytotoxicity profiling of the mansouramycins in a panel of up to 36 tumor cell lines indicated significant cytotoxicity of several derivatives, with pronounced selectivity for non-small cell lung cancer, breast cancer, melanoma, and prostate cancer cells.
Chemical composition and biological activity of ripe pumpkin fruits (Cucurbita pepo L.) cultivated in Egyptian habitats
The promising combined extract of rind and flesh was biologically studied for microbial and cytotoxic activities in comparison with the whole isolated components.
Bioactive Benzopyrone Derivatives from New Recombinant Fusant of Marine Streptomyces
- M. El-Gendy, M. Shaaban, A. El-Bondkly, K. Shaaban
- Biology, ChemistryApplied biochemistry and biotechnology
- 13 June 2008
The fermentation, isolation, as well as the biological activity of these bioactive compounds are described here as microbial products for the first time.
Hurgadacin: A new steroid from Sinularia polydactyla
Pachydictyols B and C: New Diterpenes from Dictyota dichotoma Hudson
Two new diterpenoids, pachydictyol B and C, were isolated from the dichloromethane extract of the marine brown alga, Dictyota dichotoma, collected from the Red Sea coast of Egypt and demonstrated a weak and unselective cytotoxicity against twelve human tumor cell lines with a mean IC50 of >30.0 µM.
Distribution of bacteria in Lake Qarun, AL Fayoum, Egypt (2014 -2015) in relation to its physical and hydrochemical characterization.
The bacteriological monitoring of Lake Qarun water and sediment (aerobic heterotrophs, Staphylococcus sp., Vibrio sp. Aeromonas sp., S. feacalis, E. coli, and total coliform sp.) through the period…
Bioactive Secondary Metabolites from a New Terrestrial Streptomyces sp. TN262
- L. Elleuch, M. Shaaban, H. Laatsch
- Chemistry, BiologyApplied biochemistry and biotechnology
- 20 October 2009
During our search for Streptomyces spp. as new producers of bioactive secondary metabolites, the ethyl acetate extract of the new terrestrial Streptomyces isolate TN262 delivered eight…
Four butyrolactones and diverse bioactive secondary metabolites from terrestrial Aspergillus flavipes MM2: isolation and structure determination
- Mohamed M.S. Nagia, M. El-Metwally, M. Shaaban, S. El-Zalabani, A. Hanna
- Chemistry, BiologyOrganic and medicinal chemistry letters
- 1 March 2012
The taxonomical characterization of A. flavipes MM2 along with its upscale fermentation, isolation and structural assignment of the obtained bioactive metabolites, and evaluate their antimicrobial and cytotoxic activities were described.