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Calcineurin dephosphorylates glycogen synthase kinase‐3 beta at serine‐9 in neuroblast‐derived cells
This study examined the role of calcineurin, a major calcium‐dependent protein phosphatase, in dephosphorylating Ser‐9 and activating glycogen synthase kinase‐3β (GSK‐3β). Treatment with calcineurin… Expand
Risk factors and clinical features of infections caused by plasmid-mediated AmpC beta-lactamase-producing Enterobacteriaceae.
- Y. J. Park, Sunmi Yoo, M. Seo, J. Kim, Y. K. Cho, H. Pai
- Biology, Medicine
- International journal of antimicrobial agents
- 1 July 2009
A case-control study was performed with the objective of analysing risk factors and clinical features of infections caused by plasmid-mediated AmpC beta-lactamase (plasmid AmpC)-producing… Expand
Human papillomavirus E5 protein induces expression of the EP4 subtype of prostaglandin E2 receptor in cyclic AMP response element-dependent pathways in cervical cancer cells.
Human papillomavirus (HPV) is the major cause of uterine cervical cancer, but the role of the HPV E5 in carcinogenesis is not clearly understood. Prostaglandins are known to contribute to… Expand
Potential role and mechanism of IFN-gamma inducible protein-10 on receptor activator of nuclear factor kappa-B ligand (RANKL) expression in rheumatoid arthritis
IntroductionIFN-gamma inducible protein-10 (CXCL10), a member of the CXC chemokine family, and its receptor CXCR3 contribute to the recruitment of T cells from the blood stream into the inflamed… Expand
Membrane Depolarization Induces the Undulating Phosphorylation/Dephosphorylation of Glycogen Synthase Kinase 3β, and This Dephosphorylation Involves Protein Phosphatases 2A and 2B in SH-SY5Y Human…
Changes in plasma membrane electrical potential evoke signals that regulate the expressions of various genes in the nervous system. However, the role of glycogen synthase kinase 3β (GSK-3β) in this… Expand
Stimulatory Heterotrimeric GTP-binding Protein Inhibits Hydrogen Peroxide-induced Apoptosis by Repressing BAK Induction in SH-SY5Y Human Neuroblastoma Cells*
- Soyoung Kim, M. Seo, +5 authors Y. Juhnn
- Biology, Medicine
- Journal of Biological Chemistry
- 18 January 2008
Heterotrimeric stimulatory GTP-binding protein (Gs) stimulates adenylate cyclases to activate the cAMP signaling pathway. Although the cAMP pathway has been reported to be involved in apoptosis, the… Expand
Preparation of Highly Ordered Mesoporous TiO2 Materials with Crystalline Framework from Different Mesostructured Silica Templates via Nanoreplication
Highly ordered mesoporous TiO2 materials, exhibiting crystalline frameworks and various mesostructures, have been successfully obtained via nanoreplication using various kinds of mesoporous silicas...
Inhibition of Akt/FOXO3a signaling by constitutively active FOXO3a suppresses growth of follicular thyroid cancer cell lines.
- Zhen-Yu Hong, H. J. Lee, Dong Yeob Shin, Suk Kyoung Kim, M. Seo, E. Lee
- Biology, Medicine
- Cancer letters
Akt-dependent FOXO3a cytoplasmic translocation is an important tumorigenic mechanism for escaping from apoptosis in cancer cells. In the present study, we examined whether non-phosphorylatable FOXO3a… Expand
Dibutyryl cAMP stimulates the proliferation of SH-SY5Y human neuroblastoma cells by up-regulating Skp2 protein
- Chin-ho Cho, M. Seo, Yun-il Lee, S. Kim, H. Youn, Y. Juhnn
- Medicine, Biology
- Journal of Cancer Research and Clinical Oncology
- 27 September 2006
PurposeWe previously found that the proliferation of SH-SY5Y neuroblastoma cells is stimulated when cAMP is up-regulated by stable expression of stimulatory G protein. Therefore, this study was… Expand
Therapeutic Effects of Water Soluble Danshen Extracts on Atherosclerosis
- Y. Cho, C. R. Ku, +10 authors E. Lee
- Evidence-based complementary and alternative…
- 16 January 2013
Danshen is a traditional Chinese medicine with many beneficial effects on cardiovascular diseases. The aim of this study was to evaluate the mechanisms responsible for the antiatherogenic effect of… Expand