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Biologic and clinical significance of cryoglobulins. A report of 86 cases.
- J. C. Brouet, J. Clauvel, F. Danon, M. Klein, M. Seligmann
- The American journal of medicine
- 1 November 1974
Abstract Eighty-six patients with cryoglobulinemia repeatedly underwent complete immunochemical and clinical evaluation during the course of their disease. Immunochemical analysis of the purified… Expand
Subacute and chronic myelomonocytic leukemia in children (juvenile CML). Clinical and hematologic observations, and identification of prognostic factors
The clinical and hematologic characteristics of 38 children with subacute and chronic myelomonocytic leukemia (S & CMMOL) are described, and the prognostic significance of these characteristics as… Expand
Primary antibody deficiencies
It is increasingly apparent that defective antibody responses can be the common underlying basis for a wide variety of diseases formerly thought to involve the immune system only secondarily. In a… Expand
Surface bound immunoglobulins as a cell marker in human lymphoproliferative diseases.
Membrane-bound Ig were studied by immunofluorescence methods in 116 patients with lymphoproliferative disorders. Surface Ig synthetized in vitro were studied in many patients. In 70 of 73 cases of… Expand
Immunological Classification of Acute Lymphoblastic Leukaemias: Evaluation of its Clinical Significance in a Hundred Patients
- J. C. Brouet, F. Valensi, M. Daniel, G. Flandrin, J. Preud'homme, M. Seligmann
- British journal of haematology
- 1 July 1976
Summary. The use of T and B lymphocyte markers and of different antisera raised against malignant B cells and fetal thymocytes allowed the classification of 100 patients with acute lymphoblastic… Expand
B-cell neoplasia in man.
Abstract Advances in immunology and oncology provide the basis for a unifying view of the diverse human neoplastic disorders arising from cells of the B-cell series of immunocytes. As is reflected by… Expand
B and T Cell Markers in Human Proliferative Blood Diseases and Primary Immunodeficiencies, with Special Reference to Membrane Bound Immunoglobulins
The lymphoid cells active in the immune response consist of two main populations, the bone marrow derived cells (B cells) and the thymus derived cells (T cells). In man, as well as in other species,… Expand
Alpha-Chain Disease: A New Immunoglobulin Abnormality
- M. Seligmann, F. Danon, D. Hurez, E. Mihaesco, J. Preud’homme
- Biology, Medicine
- 20 December 1968
A new type of pathological immunoglobulin was found in the serum, urine, and saliva of a young Arab patient with abdominal lymphoma and diffuse lymphoplasmacytic infiltration of the small intestine.… Expand
Induction by isoniazid and hydrallazine of antinuclear factors in mice.
The long-term oral administration of isoniazid and hydrallazine to mice resulted in a significant increase in the incidence of antinuclear factors (ANF) in C57B1/6 for both drugs and BALB/c for… Expand
Waldenström's macroglobulinemia and peripheral neuropathy: a clinical and immunologic study of 25 patients.
We investigated, by indirect immunofluorescence, the binding of monoclonal IgM to human peripheral nerve in 25 patients with Waldenström's macroglobulinemia and peripheral neuropathy. In 10 cases… Expand