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Maternal drinking during pregnancy: attention and short-term memory in 14-year-old offspring--a longitudinal prospective study.
- A. Streissguth, P. Sampson, +5 authors A. Mirsky
- Psychology, Medicine
- Alcoholism, clinical and experimental research
- 1 February 1994
A large and compelling experimental literature has documented the adverse impact of prenatal alcohol exposure on the developing brain of the offspring. This is the first report of adolescent… Expand
White matter lesions account for all age-related declines in speed but not in intelligence.
MRI scans measured white matter lesion prevalence (WMLP) in 65 people ages 65-84 years who also took 17 cognitive tests: 3 tests of general fluid intelligence, 3 of vocabulary, 2 of episodic and 3 of… Expand
In vivo measurements of lead in bone at four anatomical sites: long term occupational and consequent endogenous exposure.
- J. Erkkilä, R. Armstrong, +7 authors A. Aitio
- British journal of industrial medicine
- 1 September 1992
Measurements of bone lead concentrations in the tibia, wrist, sternum, and calcaneus were performed in vivo by x ray fluorescence on active and retired lead workers from two acid battery factories,… Expand
Agreement between Programmed Cell Death Ligand-1 Diagnostic Assays across Multiple Protein Expression Cutoffs in Non–Small Cell Lung Cancer
- M. Ratcliffe, A. Sharpe, +6 authors J. Walker
- Biology, Medicine
- Clinical Cancer Research
- 10 January 2017
Purpose: Immunotherapies targeting programmed cell death-1 (PD-1) and programmed cell death ligand-1 (PD-L1) demonstrate encouraging antitumor activity and manageable tolerability in non–small cell… Expand
Losses in gross brain volume and cerebral blood flow account for age-related differences in speed but not in fluid intelligence.
Age-related gross head size; adjusted age-related change in brain volume and carotid and basilar blood flow; as well as scores on 3 tests of fluid intelligence (gf), 2 tests of information-processing… Expand
Examining the acute effects of cediranib (RECENTIN, AZD2171) treatment in tumor models: a dynamic contrast-enhanced MRI study using gadopentate.
Cediranib (RECENTIN, AZD2171) is a highly potent inhibitor of the tyrosine kinase activity associated with all three vascular endothelial growth factor (VEGF) receptors and is currently in Phase… Expand
Potential surrogate markers of cerebral microvascular angiopathy in asymptomatic subjects at risk of stroke
Cerebral microvascular angiopathy (MVA) is associated with clinical vascular risk factors and is characterised by histological changes, including thickening of the walls of arterial vessels and… Expand
Cellular Mechanisms of Captopril‐Induced Matrix Remodeling in Syrian Hamster Cardiomyopathy
BackgroundAlthough angiotensin-converting enzyme (ACE) inhibitors have become a mainstay of treatment for chronic congestive heart failure (CHF), it is not known whether the cardiac remodeling… Expand
Magnetic resonance transverse relaxation time T2 of knee cartilage in osteoarthritis at 3-T: a cross-sectional multicentre, multivendor reproducibility study
ObjectiveThe transverse relaxation time (T2) in MR imaging has been identified as a potential biomarker of hyaline cartilage pathology. This study investigates whether MR assessments of T2 are… Expand
Inhibition of glycogenolysis enhances gluconeogenic precursor uptake by the liver of conscious dogs.
- M. Shiota, P. Jackson, +5 authors A. Cherrington
- Biology, Medicine
- The American journal of physiology
- 1 November 1997
We investigated the effect of inhibiting glycogenolysis on gluconeogenesis in 18-h-fasted conscious dogs with the use of intragastric administration of BAY R 3401, a glycogen phosphorylase inhibitor.… Expand