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Current concepts in ovarian epithelial tumorigenesis: correlation between morphological and molecular data.
TLDR
The proposed cell of origin of epithelial ovarian malignancy is discussed as well as recent molecular data relating to ovarian cancers of different morphological types, which can lead to the development of specific therapeutic agents of value against a specific tumour type. Expand
Atypical reactive proliferation of endocervix: a common lesion associated with endometrial carcinoma and likely related to prior endometrial sampling
TLDR
Atypical reactive proliferation is most likely a reactive/reparative response to recent endometrial biopsy or curettage and may be of value in cases where the uterine carcinoma is endometrioid in type as these neoplasms are generally vimentin positive. Expand
Genetic Counselling Referral Rates and Uptake of BRCA1 and BRCA2 Testing among Women Diagnosed with Serous Ovarian Cancer in a Tertiary Care Cancer Centre
TLDR
The referral rate of women with serous ovarian, fallopian tube and primary peritoneal cancers to the JCC genetics program is currently suboptimal, and stage at diagnosis and early discussion of GT were significant prognostic factors for referral. Expand
Interobserver variability amongst gastrointestinal pathologists in assessing prognostic parameters of malignant colorectal polyps: a cause for concern
TLDR
There is an urgent need to make pathologists’ assessment of MCRPs easier and more reproducible, as there was a significant variation in the assessments using the various published staging systems agreed upon on important prognostic parameters. Expand
Haematological cancers: improving outcomes. A summary of updated NICE service guidance in relation to Specialist Integrated Haematological Malignancy Diagnostic Services (SIHMDS)
TLDR
Recommendations from the systematic review and recommendations produced to form the basis for quality standards for future development of SIHMDS have relevance to the modern delivery of diagnostic services internationally. Expand
Ovarian Cancer
TLDR
Ovarian Cancer is a combination of two separate but complementary initiatives that cover the spectrum of clinical management of ovarian cancer from prevention, screening, and diagnosis to surgery, chemotherapy, and palliative care. Expand
Establishing a satellite genitourinary medicine clinic.
TLDR
A large age matched, controlled, prospective study is, however, needed to validate the impression that women attending STD clinics are a "high risk" group for cervical cytological abnormalities and that the abnormalities detected are clinically significant to warrant a policy of opportunistic screening. Expand