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Proteomic remodelling of mitochondrial oxidative pathways in pressure overload-induced heart failure.
AIMS Impairment in mitochondrial energetics is a common observation in animal models of heart failure, the underlying mechanisms of which remain incompletely understood. It was our objective toExpand
Decreased rates of substrate oxidation ex vivo predict the onset of heart failure and contractile dysfunction in rats with pressure overload.
AIMS Left ventricular hypertrophy is a risk factor for heart failure. However, it also is a compensatory response to pressure overload, accommodating for increased workload. We tested whether theExpand
Microwave-assisted digestion procedure for the determination of palladium in road dust
The present publication describes a microwave-assisted digestion procedure for the subsequent trace and ultra-trace analysis of palladium in road dust of varying origin. Digestion reagents are nitricExpand
Determination of palladium in environmental samples
Studies over the last 10 years show that the allergenic potential of palladium might be underestimated. Allergenic reactions were first reported in connection with the use of dental alloys rich inExpand
Selective determination of palladium by on-line column preconcentration and graphite furnace atomic absorption spectrometry
The present work describes a fully automated on-line column separation and preconcentration system for the determination of trace and ultratrace levels of palladium by graphite furnace atomicExpand
Adrenergic Repression of the Epigenetic Reader MeCP2 Facilitates Cardiac Adaptation in Chronic Heart Failure
Supplemental Digital Content is available in the text.
Three good reasons for heart surgeons to understand cardiac metabolism.
It is the principal goal of cardiac surgeons to improve or reinstate contractile function with, through or after a surgical procedure on the heart. Uninterrupted contractile function of the heart isExpand
NRF, a nuclear inhibitor of NF-kappaB proteins silencing interferon-beta promoter.
The family of NF-kappaB/rel transcription factors regulates a variety of promoters through specific DNA-binding sites. Consistent with the role of NF-kappaB activation as a response to pathogens, itExpand
Distribution of platinum group elements (Pt, Pd, Rh) in environmental and clinical matrices: Composition, analytical techniques and scientific outlook
Trace concentrations of the platinum group elements (PGE; here: Pt, Pd and Rh) play an important role in environmental analysis and assessment. Their importance is based on 1. their increasing use asExpand
Myocardial infarction in rats causes partial impairment in insulin response associated with reduced fatty acid oxidation and mitochondrial gene expression.
OBJECTIVE Myocardial infarction leads to contractile dysfunction. In patients with diabetes, impaired contractility has been associated with the loss of insulin effects and mitochondrial dysfunction.Expand