M. Schobert

Publications52
h-index29
Citations2,525
Highly Influential Citations199
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Virtual Footprint and PRODORIC: an integrative framework for regulon prediction in prokaryotes
TLDR
SUMMARY A new online framework for the accurate and integrative prediction of transcription factor binding sites (TFBSs) in prokaryotes was developed. Expand
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The anaerobic regulatory network required for Pseudomonas aeruginosa nitrate respiration.
In Pseudomonas aeruginosa, the narK(1)K(2)GHJI operon encodes two nitrate/nitrite transporters and the dissimilatory nitrate reductase. The narK(1) promoter is anaerobically induced in the presence… Expand
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Anaerobic adaptation in Pseudomonas aeruginosa: definition of the Anr and Dnr regulons.
The anaerobic metabolism of the opportunistic pathogen Pseudomonas aeruginosa is important for growth and biofilm formation during persistent infections. The two Fnr-type transcription factors Anr… Expand
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Characterization of a New Type of Phosphopantetheinyl Transferase for Fatty Acid and Siderophore Synthesis in Pseudomonas aeruginosa *
Phosphopantetheinyl-dependent carrier proteins are part of fatty-acid synthases (primary metabolism), polyketide synthases, and non-ribosomal peptide synthetases (secondary metabolism). For these… Expand
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An improved Escherichia coli donor strain for diparental mating.
We present a new method for diparental mating with the outstanding advantage that counterselection of the Escherichia coli donor strain is not required. This improved method uses a new donor strain,… Expand
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Long-term anaerobic survival of the opportunistic pathogen Pseudomonas aeruginosa via pyruvate fermentation.
Denitrification and arginine fermentation are central metabolic processes performed by the opportunistic pathogen Pseudomonas aeruginosa during biofilm formation and infection of lungs of patients… Expand
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Anaerobic survival of Pseudomonas aeruginosa by pyruvate fermentation requires an Usp-type stress protein.
Recently, we identified a pyruvate fermentation pathway in Pseudomonas aeruginosa sustaining anaerobic survival in the absence of alternative anaerobic respiratory and fermentative energy generation… Expand
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Anaerobic physiology of Pseudomonas aeruginosa in the cystic fibrosis lung.
  • M. Schobert, D. Jahn
  • Biology, Medicine
  • International journal of medical microbiology…
  • 1 December 2010
During chronic infection of the cystic fibrosis (CF) lung, Pseudomonas aeruginosa grows and persists in a microaerobic to anaerobic environment. P. aeruginosa is well adapted to thrive under such… Expand
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JVirGel: calculation of virtual two-dimensional protein gels
TLDR
We developed JVirGel, a collection of tools for the simulation and analysis of proteomics data based on the migration behaviour of proteins in dependence of their theoretical molecular weights in combination with their calculated isoelectric points. Expand
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Sequencing and Characterization of Pseudomonas aeruginosa phage JG004
BackgroundPhages could be an important alternative to antibiotics, especially for treatment of multiresistant bacteria as e.g. Pseudomonas aeruginosa. For an effective use of bacteriophages as… Expand
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