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RF9, a potent and selective neuropeptide FF receptor antagonist, prevents opioid-induced tolerance associated with hyperalgesia.
Neuropeptide FF (NPFF) has been proposed to play a role in pain modulation, opioid tolerance, and several other physiological processes. However, pharmacological agents that would help defineExpand
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Anti-sedative and anti-cataleptic properties of NCS-382, a γ-hydroxybutyrate receptor antagonist
NCS-382 possesses antagonistic properties at gamma-hydroxybutyrate receptor sites. Its effect on the sedative/cataleptic behaviour observed in rats after gamma-hydroxybutyrate administration wasExpand
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Influences of hepatic portal receptors on hypothalamic feeding and satiety centers.
  • M. Schmitt
  • Chemistry, Medicine
  • The American journal of physiology
  • 1 November 1973
&IMITT, n/TARU. hy%mms Uf hepi& purtd raCe@rS on @POthalamic feeding and satiety centers. Am. J. Physiol. 225(5) : IO89IO95 1973.-Evidence for a neural pathway from the hepatic portal vein to theExpand
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Effect of gamma-hydroxybutyrate and its antagonist NCS-382 on spontaneous cell firing in the prefrontal cortex of the rat
Gamma-hydroxybutyrate (GHB) at low doses (5-10 mg/kg i.p.) increased and at high doses (160-320 mg/kg i.p.) decreased the spontaneous firing rate of prefrontal cortex (PFC) neurons recorded inExpand
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Circadian rhythmicity in responses of cells in the lateral hypothalamus.
  • M. Schmitt
  • Biology, Medicine
  • The American journal of physiology
  • 1 November 1973
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Calcitonin gene-related peptide (CGRP)-immunoreactive neurons in the human cervico-thoracic paravertebral ganglia.
The occurrence of CGRP-immunoreactive neurons in human paravertebral sympathetic ganglia was investigated and CGRP-immunoreactive perikarya correlated with the distribution of structures which wereExpand
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Regulation of ion channels in rat hepatocytes
Abstract Patch-clamp studies have been performed to elucidate single ion channels in rat hepatocytes. In rat hepatocytes two types of ion channel have been identified: an inwardly rectifying K+Expand
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Decrease in Adenylate Cyclase Activity Antecedes Neurofibrillary Tangle Formation
In previous studies, the formation of cAMP was seen to be significantly reduced in various brain regions in Alzheimer patients. Recently, a staging system was introduced in which Alzheimer-related.Expand
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The reproductive tract of the male spiny mouse (Acomys cahirinus) and coagulation studies with other species.
The testes of the spiny mice showed asymmetry, the left being significantly heavier than the right (P = 0.025). Histological studies indicated that spermatozoa were first present in the testes ofExpand
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