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Identification of Circulating Fibrocytes as Precursors of Bronchial Myofibroblasts in Asthma1
The mechanisms contributing to airway wall remodeling in asthma are under investigation to identify appropriate therapeutic targets. Bronchial myofibroblasts would represent an important targetExpand
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Fibrocytes contribute to the myofibroblast population in wounded skin and originate from the bone marrow.
Myofibroblasts play a key role in wound closure but their origin is poorly understood. To investigate whether fibrocytes contribute to myofibroblast population, we examined the phenotype ofExpand
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Diagnostic work-up and outcome of cervical metastases from an unknown primary
Conclusions. An intensive diagnostic work-up including 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) detects many unknown primary tumours, leads to a low emergence rate of primaryExpand
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Direct correlation between hyperoxaluria/oxalate stone disease and the absence of the gastrointestinal tract-dwelling bacterium Oxalobacter formigenes: possible prevention by gut recolonization or
Oxalobacter formigenes is a specific oxalate-degrading, anaerobic bacterium inhabiting the gastrointestinal tracts of vertebrates, including humans. This bacterium maintains an important symbioticExpand
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'Show me the money': financial incentives increase chlamydia screening rates among tertiary students: a pilot study.
BACKGROUND We hypothesise that text-messaging and financial incentives would increase tertiary student participation in chlamydia screening. METHODS A cross-sectional study was conducted over twoExpand
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Enumeration of circulating fibrocytes for clinical use in asthma by an optimized single-platform flow cytometry assay
Background Elevated numbers of circulating fibrocytes are associated with inadequately controlled asthma, poor response to available therapies, and increased risk of adverse outcomes. The lack ofExpand
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Somatostatin receptor imaging in intracranial tumours
Abstract. The somatostatin analogue [111In-DTPA-d-Phe1]-octreotide (111In-octreotide) allows scintigraphic visualization of somatostatin receptor-expressing tissue. While it is well known that aExpand
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Interleukin (IL)-4, IL-13, and IL-17A differentially affect the profibrotic and proinflammatory functions of fibrocytes from asthmatic patients
Fibrocytes contribute to the fibrotic changes most frequently observed in forms of asthma where inflammation is driven by T helper type 2 (Th2) cells. The mechanisms that regulate the profibroticExpand
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The role of a human hematopoietic mesenchymal progenitor in wound healing and fibrotic diseases and implications for therapy.
The human peripheral blood contains a multipotent precursor that shows hematopoietic stem cell features and transiently expresses markers of the myeloid lineage. Under permissive conditions, thisExpand
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The C-C motif chemokine ligands CCL5, CCL11, and CCL24 induce the migration of circulating fibrocytes from patients with severe asthma
The C-C motif chemokine ligand 5 (CCL5), CCL11, and CCL24 are involved in the pathogenesis of asthma, and their function is mainly associated with the airway recruitment of eosinophils. This studyExpand
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