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Bacterial mutagenicity of the tranquilizing constituents of Valerianaceae roots.
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Mutagenicity studies on veterinary anabolic drugs with the Salmonella/microsome test.
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The restriction endonuclease Alu I induces chromosomal aberrations and mutations in the hypoxanthine phosphoribosyltransferase locus, but not in the Na+/K+ ATPase locus in V79 hamster cells.
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Investigation, with the Salmonella/microsome test, of psychopharmaceuticals used in meat production.
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In vitro mutagenicity of valepotriates
TLDR
The valepotriates were mutagenic for TA100, WP2 and WP2 uvrA− at concentrations up to about 1.0 μmole/plate when S9-mix was added to the test system and were toxic in the presence of a metabolic activation system for all strains tested.
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Investigation of veterinary psychopharmaceuticalwith the Salmonella/microsome test
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Microbiological studies investigating mutagenicity of deep frying fat fractions and some of their components
TLDR
The results show no mutagenic effects for the oxidized fractions of deep frying fats nor for the model test substances at higher concentrations, however, limited test reliability resulted from direct toxic effects on bacterial growth.
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Sister-chromatid exchange in Chinese hamster V79 cells exposed to quindoxin, carbadox and olaquindox.
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Formaldehyde-induced sister chromatid exchanges in vitro and the influence of the exogenous metabolizing systems S9 mix and primary rat hepatocytes
TLDR
The decrease in genotoxic effects, due to rapid metabolisation of formaldehyde in vitro and in vitro, explains the differences between results obtained in the in vitro experiments — performed without metabolizing systems — and in vivo results.
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On the in-vitro mutagenicity of caramel colours
TLDR
Commercial available caustic and ammoniated caramel colours were tested for their mutagenic potential using the Ames assay and none of the tested caramel colours showed any Mutagenic effect in the Ames test.
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