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[Preparation and evaluation of taste masked orally disintegrating tablets with granules made by the wet granulation method].
TLDR
YO was found to be a useful additive for masking unpleasant tastes and to improve the taste masking and physical characteristics of orally disintegrating tablets (ODTs) using the wet granulation method. Expand
Preparation of a PLA-PEG block copolymer using a PLA derivative with a formyl terminal group and its application to nanoparticulate formulation.
TLDR
It is suggested that PLA-aldehyde should be useful as a functional intermediate for derivatization of PLA, and PLA-(MeO-PEG(N)) can be used for the preparation of PEG-coated PLA nanoparticles. Expand
Evaluation of matrix type mucoadhesive tablets containing indomethacin for buccal application.
TLDR
The matrix type mucoadhesive tablet has good potential as a preparation for the treatment of pain due to oral aphtha. Expand
Preparation and evaluation of medicinal carbon oral films.
TLDR
It is demonstrated that ALG is useful as a film base material for the preparation of MC films, and that MC films with sufficient strength and adsorption capacities equal to those of MC powders can be produced using a physical mixture of MC and SOR on an ALG base. Expand
Comparison of physical properties and drug-releasing characteristics of white petrolatums.
TLDR
White petrolatums of Japanese Pharmacopoeia grade and Sun white marketed as a cosmetic were characterized by measuring their physical properties and drug-releasing characteristics, and Regent was the softest and the most spreadable ointment base. Expand
Antitumor characteristics of methoxypolyethylene glycol-poly(DL-lactic acid) nanoparticles containing camptothecin.
TLDR
CPT-NP are suggested to greatly improve the efficacy of CPT due to their pharmacokinetic features and showed better plasma retention, and high and long tumor localization. Expand
In vivo evaluation of Kumazasa extract and chitosan films containing the extract against deep skin ulcer model in rats.
TLDR
Reduction rate of wound area and histological features suggested that KE alone should be excellent for the promotion of wound healing, and FD films were superior as to usability such as changing the preparation. Expand
In vitro and in vivo characterization of nanoparticles made of MeO-PEG amine/PLA block copolymer and PLA.
TLDR
It is suggested that the PLA/PLA-(MeO-PEG) mixture nanoparticles with a higher PEG/PLA ratio should be useful as a carrier for the elevation of the plasma concentration of lipophilic drugs. Expand
Preparation of carboxy‐PEG‐PLA nanoparticles loaded with camptothecin and their body distribution in solid tumor–bearing mice
Carboxy‐polyethylene glycol‐poly(DL‐lactic acid) block copolymer was synthesized by reductive amination of carboxy‐polyethylene glycol‐amine and aldehyde‐ended poly(DL‐lactic acid). The obtainedExpand
[Preparation of orally disintegrating tablets for masking of unpleasant taste: comparison with corrective-adding methods].
TLDR
The results showed that orally disintegrating tablets of insoluble drugs with an unpleasant taste such as FU should be prepared with the taste masked employing the methods used in this study. Expand
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