M. Sanson

Publications69
h-index27
Citations4,185
Highly Influential Citations118
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Genome-wide association study identifies five susceptibility loci for glioma
To identify risk variants for glioma, we conducted a meta-analysis of two genome-wide association studies by genotyping 550K tagging SNPs in a total of 1,878 cases and 3,670 controls, with validation… Expand
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Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2
Neurofibromatosis type 2 (NF2) is a monogenic dominantly inherited disease predisposing carriers to develop nervous system tumours. To identify the genetic defect, the region between two flanking… Expand
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Leptomeningeal metastases from solid malignancy: a review
SummaryLeptomeningeal metastases (LMM) consist of diffuse involvement of the leptomeninges by infiltrating cancer cells. In solid tumors, the most frequent primary sites are lung and breast cancers,… Expand
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MGMT prognostic impact on glioblastoma is dependent on therapeutic modalities
MGMT promoter methylation, which has been correlated with the response to alkylating agents, was investigated in a retrospective series of 219 glioblastomas (GBMs) treated with various modalities.… Expand
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Genome-wide association study of glioma and meta-analysis
Gliomas account for approximately 80 % of all primary malignant brain tumors and, despite improvements in clinical care over the last 20 years, remain among the most lethal tumors, underscoring the… Expand
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Intracerebral administration of CpG oligonucleotide for patients with recurrent glioblastoma: a phase II study.
Immunostimulating oligodeoxynucleotides containing CpG motifs (CpG-ODN) have shown promising efficacy in cancer models when injected locally. In a phase I clinical trial, intratumoral infusions of… Expand
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Association of telomerase gene hTERT polymorphism and malignant gliomas
BackgroundThe MNS16A polymorphism is located in the downstream region of the hTERT gene and affects telomerase activity.MethodsMNS16A has been investigated as a potential risk factor and/or… Expand
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Brain lymphoma: usefulness of the magnetic resonance spectroscopy
The diagnosis of primary central nervous system lymphoma (PCNSL) should always be considered as an emergency because of the therapeutic consequences it implies. In immunocompetent patients, it relies… Expand
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The oculopharyngeal muscular dystrophy locus maps to the region of the cardiac alpha and beta myosin heavy chain genes on chromosome 14q11.2-q13.
Oculopharyngeal muscular dystrophy (OPMD) is a late-onset autosomal dominant muscular dystrophy which presents typically after the age of 50 with progressive eyelid drooping and an increasing… Expand
  • 45
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Connexin 43–mediated bystander effect in two rat glioma cell models
In tumor models, the killing by ganciclovir of a fraction of tumor cells transfected with the thymidine kinase (TK) gene has been shown to induce complete regression of the tumor. The mechanism… Expand
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