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Transmission Dynamics and Control of Severe Acute Respiratory Syndrome
TLDR
It is estimated that a single infectious case of SARS will infect about three secondary cases in a population that has not yet instituted control measures, and public-health efforts to reduce transmission are expected to have a substantial impact on reducing the size of the epidemic. Expand
Implementing an Antibiotic Stewardship Program: Guidelines by the Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America.
TLDR
These recommendations address the best approaches for antibiotic stewardship programs to influence the optimal use of antibiotics. Expand
Clarifying Adverse Drug Events: A Clinician's Guide to Terminology, Documentation, and Reporting
TLDR
The case of an actual patient is used as a framework to explain the recognition, treatment, documentation, and reporting of drug-related harm and to provide context for the more clinically useful term adverse drug reaction. Expand
Effects of body size and body composition on survival in hemodialysis patients.
TLDR
The protective effect conferred by high BMI is limited to those patients with normal or high muscle mass, and high BMI patients with inferred high body fat have increased and not decreased mortality. Expand
Methodological principles of case-control studies that analyzed risk factors for antibiotic resistance: a systematic review.
TLDR
A systematic review of case-control studies that analyzed risk factors for antibiotic-resistant organisms addressed 3 methodological principles: method of control group selection, adjustment for time at risk, and adjustment for comorbid illness. Expand
Epidemics of diarrhea caused by a clindamycin-resistant strain of Clostridium difficile in four hospitals.
TLDR
A strain of C. difficile that is highly resistant to clindamycin was responsible for large outbreaks of diarrhea in four hospitals in different states and is a specific risk factor for diarrhea due to this strain. Expand
An epidemiological investigation of a sustained high rate of pediatric parapneumonic empyema: risk factors and microbiological associations.
TLDR
The increasing incidence of empyema was associated with infection due to S. pneumoniae serotype 1, outpatient treatment with certain antibiotics, ibuprofen use, and varicella. Expand
Emergence of Antibiotic-Resistant Pseudomonas aeruginosa: Comparison of Risks Associated with Different Antipseudomonal Agents
TLDR
There were evident differences among antibiotics in the likelihood that their use would allow emergence of resistance in P. aeruginosa in patients treated with any of these drugs. Expand
Effects of protease inhibitors on hyperglycemia, hyperlipidemia, and lipodystrophy: a 5-year cohort study.
TLDR
An independent association between PI use and hyperglycemia, hyperlipidemia, and lipodystrophy is found that is not explained by the antiviral and therapeutic effect of PIs. Expand
Antimicrobial Use and Antimicrobial Resistance: A Population Perspective
TLDR
For infections like tuberculosis, prevention of antimicrobial resistance in individual hosts is a primary method of preventing the spread of resistant organisms in the community, and indirect, population-level mechanisms of selection account for the increase in the prevalence of resistance. Expand
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